Claudin 7 anticorps (C-Term)

N° du produit ABIN951552

Détail du produit anti-Claudin 7 anticorps

Antigène: Claudin 7 (CLDN7)

Épitope: AA 179-209, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to CLDN7.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 179-209 amino acids from the C-terminal region of human CLDN7

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Claudin 7

Antigène: Claudin 7 (CLDN7)

Autre désignation: Claudin-7 / CLDN7 (CLDN7 Produits)

Synonymes: anticorps cb388, anticorps claudin7, anticorps cldn7, anticorps wu:fd19f08, anticorps MGC53400, anticorps MGC75689, anticorps CLDN7, anticorps CEPTRL2, anticorps CLDN-7, anticorps CPETRL2, anticorps Hs.84359, anticorps claudin-1, anticorps claudin 7b, anticorps claudin 7 L homeolog, anticorps claudin 7, anticorps cldn7b, anticorps cldn7.L, anticorps cldn7, anticorps CLDN7, anticorps Cldn7

Sujet: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.Synonyms: CEPTRL2, CLDN-7, CPETRL2

Poids moléculaire: 22418 Da

ID gène: 1366

NCBI Accession: NP_001171951

Pathways: Hepatitis C