FXYD5 anticorps (Middle Region)

N° du produit ABIN952009

Détail du produit anti-FXYD5 anticorps

Antigène: FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))

Épitope: AA 70-100, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FXYD5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes Human Dysadherin / FXYD5 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 70-100 amino acids from the Central region of Human Dysadherin / FXYD5

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur FXYD5

Antigène: FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))

Autre désignation: Dysadherin / FXYD5 (FXYD5 Produits)

Synonymes: anticorps FXYD5, anticorps DYSAD, anticorps IWU1, anticorps KCT1, anticorps OIT2, anticorps PRO6241, anticorps RIC, anticorps EF-8, anticorps Oit2, anticorps FXYD domain containing ion transport regulator 5, anticorps FXYD domain-containing ion transport regulator 5, anticorps FXYD5, anticorps Fxyd5

Sujet: This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, is a glycoprotein that functions in the up-regulation of chemokine production, and it is involved in the reduction of cell adhesion via its ability to down-regulate E-cadherin. It also promotes metastasis, and has been linked to a variety of cancers. Alternative splicing results in multiple transcript variants. [RefSeq curation by Kathleen J. Sweadner, Ph.D., sweadner@helix.mgh.harvard.edu.].Synonyms: DYSAD, FXYD domain-containing ion transport regulator 5, IWU1

ID gène: 53827

NCBI Accession: NP_001158077