FGD4 anticorps (N-Term)

N° du produit ABIN952304

Détail du produit anti-FGD4 anticorps

Antigène: FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))

Épitope: AA 156-186, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGD4 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to FGD4.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 156-186 amino acids from the N-terminal region of human FGD4

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur FGD4

Antigène: FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))

Autre désignation: FGD4 (FGD4 Produits)

Synonymes: anticorps CMT4H, anticorps FRABP, anticorps ZFYVE6, anticorps 9030023J02Rik, anticorps 9330209B17Rik, anticorps Frabp, anticorps FYVE, RhoGEF and PH domain containing 4, anticorps FGD4, anticorps Fgd4

Sujet: This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. [provided by RefSeq].Synonyms: Actin filament-binding protein frabin, FGD1-related F-actin-binding protein, FRABP, FYVE, Frabin, RhoGEF and PH domain-containing protein 4, ZFYVE6, Zinc finger FYVE domain-containing protein 6

Poids moléculaire: 86626 Da

ID gène: 121512

NCBI Accession: NP_640334

Pathways: Neurotrophin Signaling Pathway