KREMEN2 anticorps (Middle Region)

N° du produit ABIN953114

Détail du produit anti-KREMEN2 anticorps

Antigène: KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))

Épitope: AA 247-276, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KREMEN2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to KREMEN2.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 247-276 amino acids from the Central region of human KREMEN2

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur KREMEN2

Antigène: KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))

Autre désignation: Kremen Protein 2 (KREMEN2 Produits)

Synonymes: anticorps krm2, anticorps KREMEN2, anticorps MGC147633, anticorps KRM2, anticorps 2900054E04Rik, anticorps Krm2, anticorps kringle containing transmembrane protein 2 S homeolog, anticorps kringle containing transmembrane protein 2, anticorps kremen2.S, anticorps KREMEN2, anticorps kremen2, anticorps Kremen2

Sujet: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.Synonyms: Dickkopf receptor 2, KREMEN2, KRM2, Kringle domain-containing transmembrane protein 2, Kringle-containing protein marking the eye and the nose

ID gène: 79412

NCBI Accession: NP_078783

Pathways: Signalisation WNT