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TBC1D3E (AA 497-527), (C-Term) anticorps

Détails pour le produit réf. ABIN955097, Fournisseur: Connectez-vous pour afficher
Antigène
Épitope
C-Term, AA 497-527
11
7
3
Reactivité
Humain
12
Hôte
Lapin
12
Clonalité
Polyclonal
Conjugué
Inconjugué
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
11
8
Fournisseur
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Supplier Product No.
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Immunogène KLH conjugated synthetic peptide between 497-527 amino acids from the C-terminal region of human TBC1D3E
Isotype Ig
Specificité This antibody reacts to TBC1D3E.
Réactivité croisée (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Sujet BC1D3E acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity).Synonyms: TBC1 domain family member 3E/3F
Poids moléculaire 62199 Da
ID gène 84218
NCBI Accession NP_115634
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-TBC1D3E (AA 497-527), (C-Term) anticorps (ABIN955097) TBC1D3E Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35µg/l...
Reference: Background Alkan, Kidd, Marques-Bonet et al.: "Personalized copy number and segmental duplication maps using next-generation sequencing." dans: Nature genetics, Vol. 41, Issue 10, pp. 1061-7, 2009 (PubMed).

Wainszelbaum, Charron, Kong et al.: "The hominoid-specific oncogene TBC1D3 activates Ras and modulates epidermal growth factor receptor signaling and trafficking." dans: The Journal of biological chemistry, Vol. 283, Issue 19, pp. 13233-42, 2008 (PubMed).

Hodzic, Kong, Wainszelbaum et al.: "TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12." dans: Genomics, Vol. 88, Issue 6, pp. 731-6, 2006 (PubMed).

Zody, Garber, Adams et al.: "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. ..." dans: Nature, Vol. 440, Issue 7087, pp. 1045-9, 2006 (PubMed).

Paulding, Ruvolo, Haber: "The Tre2 (USP6) oncogene is a hominoid-specific gene." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 5, pp. 2507-11, 2003 (PubMed).