ARL6 anticorps (N-Term)

N° du produit ABIN965594

Détail du produit anti-ARL6 anticorps

Antigène: ARL6 (ADP Ribosylation Factor Like GTPase 6 (ARL6))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARL6 est non-conjugé

Application: Immunohistochemistry (IHC)

Purification: Purified by antigen-specific affinity chromatography.

Immunogène: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human ARL6 (ADP-ribosylation factorlike protein 6)

Information d'application

Indications d'application: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-ARL6 (ABIN965594)

Chiang, Nishimura, Searby, Elbedour, Carmi, Ferguson, Secrist, Braun, Casavant, Stone, Sheffield: "Comparative genomic analysis identifies an ADP-ribosylation factor-like gene as the cause of Bardet-Biedl syndrome (BBS3)." dans: American journal of human genetics, Vol. 75, Issue 3, pp. 475-84, (2004) (PubMed).

Fan, Esmail, Ansley, Blacque, Boroevich, Ross, Moore, Badano, May-Simera, Compton, Green, Lewis, van Haelst, Parfrey, Baillie, Beales, Katsanis, Davidson, Leroux: "Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome." dans: Nature genetics, Vol. 36, Issue 9, pp. 989-93, (2004) (PubMed).

Ingley, Williams, Walker, Tsai, Colley, Sayer, Tilbrook, Sarna, Beaumont, Klinken: "A novel ADP-ribosylation like factor (ARL-6), interacts with the protein-conducting channel SEC61beta subunit." dans: FEBS letters, Vol. 459, Issue 1, pp. 69-74, (1999) (PubMed).

Jacobs, Schilf, Fliegert, Koling, Weber, Schürmann, Joost: "ADP-ribosylation factor (ARF)-like 4, 6, and 7 represent a subgroup of the ARF family characterization by rapid nucleotide exchange and a nuclear localization signal." dans: FEBS letters, Vol. 456, Issue 3, pp. 384-8, (1999) (PubMed).

Détails sur ARL6

Antigène: ARL6 (ADP Ribosylation Factor Like GTPase 6 (ARL6))

Autre désignation: ARL6 (ARL6 Produits)

Synonymes: anticorps BBS3, anticorps RP55, anticorps 1110018H24Rik, anticorps 2210411E14Rik, anticorps zgc:101762, anticorps arl6, anticorps ADP ribosylation factor like GTPase 6, anticorps ADP-ribosylation factor-like 6, anticorps ADP-ribosylation factor like GTPase 6, anticorps ADP-ribosylation factor-like protein 6, anticorps ADP ribosylation factor like GTPase 6 L homeolog, anticorps ARL6, anticorps Arl6, anticorps arl6, anticorps arl-6, anticorps arl6.L

Sujet: ARL6 (ADP-ribosylation factor-like protein 6) belongs to the ARF family of GTP-binding proteins. ARF proteins are important regulators of cellular traffic and are the founding members of an expanding family of homologous proteins and genomic sequences. They depart from other small GTP-binding proteins by a unique structural device that implements front-back communication from the N-terminus to the nucleotide-binding site. Studies of the mouse ortholog of this protein suggest an involvement in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation.