Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human AXL(Tyrosine-protein kinase receptor UFO)
AXL
Reactivité: Humain
WB, IP
Hôte: Lapin
Polyclonal
unconjugated
Restrictions
For Research Use only
Stock
4 °C
Shimojima, Takada, Ebihara, Neumann, Fujioka, Irimura, Jones, Feldmann, Kawaoka: "Tyro3 family-mediated cell entry of Ebola and Marburg viruses." dans: Journal of virology, Vol. 80, Issue 20, pp. 10109-16, (2006) (PubMed).
Craven, Xu, Weiner, Fridell, Dent, Srivastava, Varnum, Liu, Cance: "Receptor tyrosine kinases expressed in metastatic colon cancer." dans: International journal of cancer. Journal international du cancer, Vol. 60, Issue 6, pp. 791-7, (1995) (PubMed).
Lee, Strunk, Spritz: "A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes." dans: Oncogene, Vol. 8, Issue 12, pp. 3403-10, (1993) (PubMed).
Partanen, Mäkelä, Alitalo, Lehväslaiho, Alitalo: "Putative tyrosine kinases expressed in K-562 human leukemia cells." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 22, pp. 8913-7, (1991) (PubMed).
OBryan, Frye, Cogswell, Neubauer, Kitch, Prokop, Espinosa, Le Beau, Earp, Liu: "axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase." dans: Molecular and cellular biology, Vol. 11, Issue 10, pp. 5016-31, (1991) (PubMed).
Janssen, Schulz, Steenvoorden, Schmidberger, Strehl, Ambros, Bartram: "A novel putative tyrosine kinase receptor with oncogenic potential." dans: Oncogene, Vol. 6, Issue 11, pp. 2113-20, (1991) (PubMed).
anticorps JTK11, anticorps UFO, anticorps AI323647, anticorps Ark, anticorps Tyro7, anticorps Ufo, anticorps AXL receptor tyrosine kinase, anticorps Axl receptor tyrosine kinase, anticorps AXL, anticorps Axl
Sujet
AXL(Tyrosine-protein kinase receptor UFO) may function as a signal transducer between specific cell types of mesodermal origin. In case of filovirus infection, AXL seems to function as a cell entry factor. AXL is heterodimer and heterotetramer with GAS6. AXL is a single-pass type I membrane protein. It is highly expressed in metastatic colon tumors. And weakly expressed in normal colon tissue. AXL belongs to the protein kinase superfamily and Tyr protein kinase family and AXL/UFO subfamily. AXL contains 1 protein kinase domain. Synonyms: UFO