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Calpain 3 anticorps (C-Term)

CAPN3 Reactivité: Humain IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN965743
  • Antigène Voir toutes Calpain 3 (CAPN3) Anticorps
    Calpain 3 (CAPN3)
    Épitope
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 26
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 25
    • 2
    Lapin
    Clonalité
    • 25
    • 2
    Polyclonal
    Conjugué
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Calpain 3 est non-conjugé
    Application
    • 18
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC)
    Purification
    Purified by antigen-specific affinity chromatography.
    Immunogène
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human CAPN3(Calpain-3)
    Top Product
    Discover our top product CAPN3 Anticorps primaire
  • Indications d'application
    ELISA, Western blotting: 1µg/ml for 2hrs.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    This antibody is stored in PBS, 50% glycerol
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Antigène
    Calpain 3 (CAPN3)
    Autre désignation
    CAPN3 (CAPN3 Produits)
    Synonymes
    anticorps capn3, anticorps MGC80925, anticorps zgc:92687, anticorps CAPN3, anticorps AI323605, anticorps Capa-3, anticorps Capa3, anticorps Lp82, anticorps p94, anticorps Lp84, anticorps Lp85, anticorps CANP3, anticorps CANPL3, anticorps LGMD2, anticorps LGMD2A, anticorps nCL-1, anticorps SKM-CALP, anticorps SKM-CALPOV, anticorps nCL1, anticorps calpain 1, (mu/I) large subunit L homeolog, anticorps calpain 3a, (p94), anticorps calpain 3, anticorps capn1.L, anticorps capn3a, anticorps CAPN3, anticorps Capn3
    Sujet
    CAPN3(Calpain-3) is a calcium-regulated non-lysosomal thiol-protease. It has a broad endopeptidase specificity. CAPN3 is activated by micromolar concentrations of calcium and inhibited by calpastatin. It interacts with TTN/titin. Isoform I is skeletal muscle specific. Defects in CAPN3 are the cause of limb-girdle muscular dystrophy type 2A (LGMD2A). LGMD2A is both autosomal dominantly and recessively transmitted. It is characterized by progressive symmetrical atrophy and weakness of the proximal limb muscles and elevated serum creatine kinase. CAPN3 belongs to the peptidase C2 family and contains 1 calpain catalytic domain and 4 EF-hand domains.
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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