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Calpain 3 anticorps (C-Term)
CAPN3
Reactivité: Humain
IHC
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-Calpain 3 anticorps
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Antigène
Voir toutes Calpain 3 (CAPN3) Anticorps
Calpain 3 (CAPN3)
Épitope
Tous les épitopes à travers Calpain 3 Anticorps.
C-Term
Reactivité
Toutes les réactivités sur Calpain 3 Anticorps
Humain
Hôte
Toutes les hôtes sur Calpain 3 Anticorps
Lapin
Clonalité
Toutes les clonalités sur Calpain 3 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers Calpain 3 Anticorps
Cet anticorp Calpain 3 est non-conjugé
Application
Tous les applications à travers Calpain 3 Anticorps.
Immunohistochemistry (IHC)
Purification
Purified by antigen-specific affinity chromatography.
Immunogène
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human CAPN3(Calpain-3)
Top Product
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Alternatives
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Information d'application
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Indications d'application
ELISA, Western blotting: 1µg/ml for 2hrs.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
This antibody is stored in PBS, 50% glycerol
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Détails sur Calpain 3
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Antigène
Calpain 3 (CAPN3)
Autre désignation
CAPN3 (CAPN3 Produits )
Synonymes
anticorps capn3, anticorps MGC80925, anticorps zgc:92687, anticorps CAPN3, anticorps AI323605, anticorps Capa-3, anticorps Capa3, anticorps Lp82, anticorps p94, anticorps Lp84, anticorps Lp85, anticorps CANP3, anticorps CANPL3, anticorps LGMD2, anticorps LGMD2A, anticorps nCL-1, anticorps SKM-CALP, anticorps SKM-CALPOV, anticorps nCL1, anticorps calpain 1, (mu/I) large subunit L homeolog, anticorps calpain 3a, (p94), anticorps calpain 3, anticorps capn1.L, anticorps capn3a, anticorps CAPN3, anticorps Capn3
Sujet
CAPN3(Calpain-3) is a calcium-regulated non-lysosomal thiol-protease. It has a broad endopeptidase specificity. CAPN3 is activated by micromolar concentrations of calcium and inhibited by calpastatin. It interacts with TTN/titin. Isoform I is skeletal muscle specific. Defects in CAPN3 are the cause of limb-girdle muscular dystrophy type 2A (LGMD2A). LGMD2A is both autosomal dominantly and recessively transmitted. It is characterized by progressive symmetrical atrophy and weakness of the proximal limb muscles and elevated serum creatine kinase. CAPN3 belongs to the peptidase C2 family and contains 1 calpain catalytic domain and 4 EF-hand domains.
Pathways
Regulation of Muscle Cell Differentiation , Skeletal Muscle Fiber Development
Vus récemment
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