CDC42 anticorps (AA 121-138)

N° du produit ABIN965836

Détail du produit anti-CDC42 anticorps

Antigène: CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))

Épitope: AA 121-138

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Veuillez nous consulter SVP

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC42 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Immunogène: A synthetic peptide corresponding to a sequence at the middle region of human CDC42 (121-138aa), identical to the related mouse and rat sequence.

Information d'application

Restrictions: For Research Use only

Stockage

Reconstitution: 0.2ml of distilled water will yield a concentration of 500µg/ml.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Stock: -20 °C

Détails sur CDC42

Antigène: CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))

Autre désignation: CDC42 (CDC42 Produits)

Synonymes: anticorps CDC42Hs, anticorps G25K, anticorps AI747189, anticorps AU018915, anticorps cdc42a, anticorps wu:fb07d08, anticorps wu:fj62g06, anticorps zgc:63918, anticorps Xcdc42, anticorps cdc42hs, anticorps g25k, anticorps CDC42, anticorps CG12530, anticorps Cdc42Dm, anticorps D-CDC42, anticorps D-Cdc42, anticorps D-cdc42, anticorps DCDC42, anticorps DCdc42, anticorps Dcdc42, anticorps Dm Cdc42, anticorps DmCDC42, anticorps Dmcdc42, anticorps Dmel\\CG12530, anticorps cdc42, anticorps cell division cycle 42, anticorps Cell division control protein 42 homolog, anticorps cell division control protein 42 homolog, anticorps cell division cycle 42 L homeolog, anticorps CG12530 gene product from transcript CG12530-RC, anticorps Rho family GTPase, anticorps CDC42, anticorps Cdc42, anticorps cdc42, anticorps LOC100636735, anticorps LOC100637699, anticorps LOC100638834, anticorps cdc42.L

Sujet: Cell division control protein 42 homolog also known as CDC42 is a protein involved in regulation of the cell cycle. In humans, CDC42 is encoded by the CDC42 gene.CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.

Pathways: Signalisation MAPK, Dynamique des Microtubules, Signalisation RTK, Signalisation WNT, TCR Signaling, EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Signaling Events mediated by VEGFR1 and VEGFR2, EGFR Downregulation, VEGF Signaling