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CHEK2 anticorps

CHEK2 Reactivité: Humain, Souris, Rat IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN965891
  • Antigène Voir toutes CHEK2 Anticorps
    CHEK2 (Checkpoint Kinase 2 (CHEK2))
    Reactivité
    • 262
    • 97
    • 83
    • 16
    • 14
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 242
    • 21
    • 1
    • 1
    Lapin
    Clonalité
    • 228
    • 37
    Polyclonal
    Conjugué
    • 117
    • 14
    • 12
    • 12
    • 12
    • 12
    • 12
    • 12
    • 10
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp CHEK2 est non-conjugé
    Application
    • 207
    • 80
    • 79
    • 72
    • 37
    • 37
    • 33
    • 28
    • 28
    • 19
    • 18
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Specificité
    Chk2 (Ab-68) antibody detects endogenous levels of total Chk2 protein.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogène
    The antiserum was produced against synthesized non-phosphopeptide derived from human Chk2 around the phosphorylation site of threonine 68.
    Top Product
    Discover our top product CHEK2 Anticorps primaire
  • Indications d'application
    WB: 1:500~1:1000
    IHC: 1:50~1:100.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    100ug/100ul.
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Bhoumik, Takahashi, Breitweiser, Shiloh, Jones, Ronai: "ATM-dependent phosphorylation of ATF2 is required for the DNA damage response." dans: Molecular cell, Vol. 18, Issue 5, pp. 577-87, (2005) (PubMed).

    Gorgoulis, Vassiliou, Karakaidos, Zacharatos, Kotsinas, Liloglou, Venere, Ditullio, Kastrinakis, Levy, Kletsas, Yoneta, Herlyn, Kittas, Halazonetis: "Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions." dans: Nature, Vol. 434, Issue 7035, pp. 907-13, (2005) (PubMed).

    Jin, Kurosu, Yamaguchi, Arai, Miura: "Hematopoietic cytokines enhance Chk1-dependent G2/M checkpoint activation by etoposide through the Akt/GSK3 pathway to inhibit apoptosis." dans: Oncogene, Vol. 24, Issue 12, pp. 1973-81, (2005) (PubMed).

    Li, Stern: "Regulation of CHK2 by DNA-dependent protein kinase." dans: The Journal of biological chemistry, Vol. 280, Issue 12, pp. 12041-50, (2005) (PubMed).

  • Antigène
    CHEK2 (Checkpoint Kinase 2 (CHEK2))
    Autre désignation
    CHK2 (CHEK2 Produits)
    Synonymes
    anticorps CDS1, anticorps CHK2, anticorps HuCds1, anticorps LFS2, anticorps PP1425, anticorps RAD53, anticorps hCds1, anticorps fa66f08, anticorps wu:fa66f08, anticorps zgc:55865, anticorps Cds1, anticorps HUCDS1, anticorps Rad53, anticorps Chk2, anticorps cds1, anticorps chek2, anticorps chk2, anticorps hucds1, anticorps lfs2, anticorps pp1425, anticorps rad53, anticorps checkpoint kinase 2, anticorps serine/threonine-protein kinase chk2, anticorps checkpoint kinase 2 L homeolog, anticorps CHEK2, anticorps chek2, anticorps Chek2, anticorps MCYG_07308, anticorps chek2.L
    Pathways
    Signalisation p53, Apoptose, Cycle Cellulaire
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