Connexin 43/GJA1 anticorps

N° du produit ABIN965918

Détail du produit anti-Connexin 43/GJA1 anticorps

Antigène: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Connexin 43/GJA1 est non-conjugé

Application: Immunohistochemistry (IHC)

Specificité: Connexin43 (Ab-367) antibody detects endogenous levels of total Connexin43 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized phosphopeptide derived from human Connexin43 around the phosphorylation site of serine 367 (R-A-SP-S-R).

Information d'application

Indications d'application: WB: 1:500~1:1000
IHC: 1:50~1:100.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-Connexin 43/GJA1 (ABIN965918)

Matsushita, Kurihara, Watanabe, Okada, Sakai, Amano: "Alterations of phosphorylation state of connexin 43 during hypoxia and reoxygenation are associated with cardiac function." dans: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 54, Issue 3, pp. 343-53, (2006) (PubMed).

Bao, Altenberg, Reuss: "Mechanism of regulation of the gap junction protein connexin 43 by protein kinase C-mediated phosphorylation." dans: American journal of physiology. Cell physiology, Vol. 286, Issue 3, pp. C647-54, (2004) (PubMed).

Solan, Fry, TenBroek, Lampe: "Connexin43 phosphorylation at S368 is acute during S and G2/M and in response to protein kinase C activation." dans: Journal of cell science, Vol. 116, Issue Pt 11, pp. 2203-11, (2003) (PubMed).

Li, Waldo, Linask, Chen, Wessels, Parmacek, Kirby, Lo: "An essential role for connexin43 gap junctions in mouse coronary artery development." dans: Development (Cambridge, England), Vol. 129, Issue 8, pp. 2031-42, (2002) (PubMed).

Détails sur Connexin 43/GJA1

Antigène: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Autre désignation: Connexin 43 (GJA1 Produits)

Synonymes: anticorps AVSD3, anticorps CX43, anticorps DFNB38, anticorps GJAL, anticorps HLHS1, anticorps HSS, anticorps ODDD, anticorps Cx43, anticorps AU042049, anticorps AW546267, anticorps Cnx43, anticorps Cx43alpha1, anticorps Gja-1, anticorps Npm1, anticorps connexin43, anticorps cx43a1, anticorps gja1, anticorps zfCx43.3, anticorps connexin 43, anticorps gja1-A, anticorps cx43, anticorps gjal, anticorps oddd, anticorps dfnb38, anticorps gap junction protein alpha 1, anticorps gap junction protein, alpha 1, anticorps connexin 43, anticorps gap junction protein alpha 1 L homeolog, anticorps CONNEXIN 43 protein, anticorps GJA1, anticorps Gja1, anticorps cx43, anticorps gja1.L, anticorps gja1, anticorps CONNEXIN 43

Pathways: Signalisation MAPK, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization