Elf4 anticorps (C-Term)

N° du produit ABIN966054

Détail du produit anti-Elf4 anticorps

Antigène: Elf4 (E74 like ETS transcription factor 4 (Elf4))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Elf4 est non-conjugé

Application: Immunohistochemistry (IHC)

Purification: Purified by antigen-specific affinity chromatography.

Immunogène: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human ELF4 (ETS-related transcription factor Elf-4)

Information d'application

Indications d'application: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur Elf4

Antigène: Elf4 (E74 like ETS transcription factor 4 (Elf4))

Autre désignation: ELF4 (Elf4 Produits)

Synonymes: anticorps ELF4, anticorps RGD1560743, anticorps ELFR, anticorps MEF, anticorps AV314029, anticorps BC042423, anticorps ENSMUSG00000053512, anticorps Gm9907, anticorps Mef, anticorps E74 like ETS transcription factor 4, anticorps E74-like factor 4 (ets domain transcription factor), anticorps ELF4, anticorps Elf4

Sujet: ELF4 (ETS-related transcription factor Elf-4) is a transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. It acts synergistically with RUNX1 to transactivate the IL3 promoter. ELF4 also transactivates the PRF1 promoter in natural killer (NK) cells. The protein plays a role in the development and function of NK and NK T-cells and in innate immunity. ELF4 interacts via an N-terminal region with the RUNX1 Runt domain and interacts via its C-terminus with PML, this interaction enhances ELF4 transactivation of the bovine lysozyme gene.

Pathways: Positive Regulation of Endopeptidase Activity