FANCG anticorps (C-Term)

N° du produit ABIN966129

Détail du produit anti-FANCG anticorps

Antigène: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FANCG est non-conjugé

Application: Immunohistochemistry (IHC)

Immunogène: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human FANCG (Fanconi anemia group G protein)

Information d'application

Restrictions: For Research Use only

Stockage

Stock: 4 °C

Références pour anticorps anti-FANCG (ABIN966129)

Meetei, Levitus, Xue, Medhurst, Zwaan, Ling, Rooimans, Bier, Hoatlin, Pals, de Winter, Wang, Joenje: "X-linked inheritance of Fanconi anemia complementation group B." dans: Nature genetics, Vol. 36, Issue 11, pp. 1219-24, (2004) (PubMed).

Demuth, Wlodarski, Tipping, Morgan, de Winter, Thiel, Gräsl, Schindler, DAndrea, Altay, Kayserili, Zatterale, Kunze, Ebell, Mathew, Joenje, Sperling, Digweed: "Spectrum of mutations in the Fanconi anaemia group G gene, FANCG/XRCC9." dans: European journal of human genetics : EJHG, Vol. 8, Issue 11, pp. 861-8, (2000) (PubMed).

Garcia-Higuera, Kuang, Näf, Wasik, DAndrea: "Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex." dans: Molecular and cellular biology, Vol. 19, Issue 7, pp. 4866-73, (1999) (PubMed).

Détails sur FANCG

Antigène: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Autre désignation: FANCG (FANCG Produits)

Synonymes: anticorps xFANCG, anticorps FAG, anticorps XRCC9, anticorps AU041407, anticorps Xrcc9, anticorps Fanconi anemia complementation group G S homeolog, anticorps Fanconi anemia complementation group G, anticorps Fanconi anemia, complementation group G, anticorps fancg.S, anticorps FANCG, anticorps Fancg

Sujet: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. FANCG may be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. FANCG is a andidate tumor suppressor gene. FANCG belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. The complex is not found in FA patients. The major form is nuclear. The minor form is cytoplasmic. Highly expressed in testis and thymus. Found in lymphoblasts. Defects in FANCG are a cause of Fanconi anemia (FA)
Synonym: XRCC9 (DNA repair protein XRCC9)

Pathways: Réparation de l'ADN