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FCER2 anticorps

FCER2 Reactivité: Humain FACS, ELISA Hôte: Souris Monoclonal 5B5 unconjugated
N° du produit ABIN966132
  • Antigène Voir toutes FCER2 Anticorps
    FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
    Reactivité
    • 105
    • 58
    • 11
    Humain
    Hôte
    • 64
    • 47
    • 24
    Souris
    Clonalité
    • 91
    • 42
    • 2
    Monoclonal
    Conjugué
    • 58
    • 18
    • 12
    • 9
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FCER2 est non-conjugé
    Application
    • 82
    • 55
    • 36
    • 21
    • 16
    • 13
    • 10
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), ELISA
    Purification
    Ascitic fluid
    Immunogène
    Purified recombinant fragment of human FCER2 expressed in E. Coli.
    Clone
    5B5
    Isotype
    IgG1
    Top Product
    Discover our top product FCER2 Anticorps primaire
  • Indications d'application
    Flow cytometry: 1/200 - 1/400.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
  • Bertram: "Fluid flow in distensible vessels." dans: Clinical and experimental pharmacology & physiology, Vol. 36, Issue 2, pp. 206-16, (2009) (PubMed).

    Shen, Vermeulen, Rajaraman, Menashe, He, Chapman, Yeager, Thomas, Burdett, Hutchinson, Yuenger, Chanock, Lan: "Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China." dans: Environmental and molecular mutagenesis, Vol. 50, Issue 4, pp. 285-90, (2009) (PubMed).

    Carvalho, Fullen, Lowe, Su, Ma: "Comparison of CD23 staining patterns in Merkel cell carcinoma and non-cutaneous small cell carcinoma." dans: Journal of cutaneous pathology, Vol. 36, Issue 2, pp. 206-10, (2009) (PubMed).

  • Antigène
    FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
    Autre désignation
    FCER2 (FCER2 Produits)
    Synonymes
    anticorps BLAST-2, anticorps CD23, anticorps CD23A, anticorps CLEC4J, anticorps FCE2, anticorps IGEBF, anticorps Fcer2a, anticorps Fc fragment of IgE receptor II, anticorps FCER2, anticorps Fcer2
    Sujet
    The human leukocyte differentiation antigen CD23 (FCE2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor.(supplied by OMIM) . It is expressed on most mature, conventional B cells (but not on peritoneal CD5+ B cells), and can also be found on the surface of T cells, macrophages, platelets and EBV transformed B lymphoblasts. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic Lymphocytic leukemia. CD23 is expressed by B cells in the follicular mantle but not by proliferating germinal centre cells. CD23 is also expressed by eosinophils. CD23 is distinct from the high affinity IgE receptors found on basophils and mast cells, which mediate allergic reactions. The low affinity receptors are thought to play a role in isotype specific immunoregulation. The regulation of CD23 surface expression appears to be integral with the complex IgE system, which involves interactions of cells, cytokines, antibodies and regulatory factors. CD23 has been described as a membrane bound cytokine, in that the soluble cleavage products of CD23 are themselves able to act as cytokines in vitro.
    Synonyms: CD23, FCE2, CD23A, IGEBF, CLEC4J, FCER2
    Poids moléculaire
    37kDa
    ID gène
    2208
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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