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FES anticorps

FES Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 5A11G5 unconjugated
N° du produit ABIN966135
  • Antigène Voir toutes FES Anticorps
    FES (Feline Sarcoma Oncogene (FES))
    Reactivité
    • 38
    • 21
    • 14
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 35
    • 4
    • 1
    Souris
    Clonalité
    • 37
    • 3
    Monoclonal
    Conjugué
    • 26
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp FES est non-conjugé
    Application
    • 25
    • 11
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Ascitic fluid
    Immunogène
    Purified recombinant fragment of FES expressed in E. Coli.
    Clone
    5A11G5
    Isotype
    IgG1
    Top Product
    Discover our top product FES Anticorps primaire
  • Indications d'application
    Western Bloting: 1/500 - 1/2000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
  • Vitenzon, Mironov, Petrushanskaya: "Functional electrostimulation of muscles as a method for restoring motor functions." dans: Neuroscience and behavioral physiology, Vol. 35, Issue 7, pp. 709-14, (2006) (PubMed).

  • Antigène
    FES (Feline Sarcoma Oncogene (FES))
    Autre désignation
    FES (FES Produits)
    Synonymes
    anticorps FPS, anticorps RGD1564385, anticorps AI586313, anticorps BB137047, anticorps c-fes, anticorps FES, anticorps c-fps, anticorps FES proto-oncogene, tyrosine kinase, anticorps feline sarcoma oncogene, anticorps FES, anticorps Fes, anticorps fes
    Sujet
    FES (feline sarcoma oncogene) and Fer are the only two members of a unique family of cytoplasmic protein tyrosine kinases. FES and Fer contain a central Src homology-2 (SH2) domain and a carboxy-terminal tyrosine kinase catalytic domain. They are structurally distinguished from other members of cytoplasmic protein tyrosine kinase subfamilies by the presence of amino-terminal Fer/CIP4 homology and coiled-coil domains. FES was originally identified as an oncogene from avian and feline retroviruses. Human c-Fes has been implicated in myeloid, vascular endothelial and neuronal cell differentiation. FES has tyrosinespecific protein kinase activity and that activity is required for maintenance of cellular transformation. Mutations may activate the FES kinase and thereby contribute to cancer. However, recent data strongly suggests that the c-FES protein-tyrosine kinase is a tumor suppressor rather than a dominant oncogene in colorectal cancer.
    Synonyms: FPS
    ID gène
    2242
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Signaling Events mediated by VEGFR1 and VEGFR2
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