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FOXO1 anticorps

FOXO1 Reactivité: Humain, Souris, Rat IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN966149
  • Antigène Voir toutes FOXO1 Anticorps
    FOXO1 (Forkhead Box O1 (FOXO1))
    Reactivité
    • 231
    • 162
    • 151
    • 48
    • 30
    • 25
    • 18
    • 11
    • 9
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 212
    • 21
    • 1
    • 1
    Lapin
    Clonalité
    • 205
    • 30
    Polyclonal
    Conjugué
    • 105
    • 11
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FOXO1 est non-conjugé
    Application
    • 198
    • 91
    • 78
    • 66
    • 57
    • 57
    • 44
    • 33
    • 20
    • 20
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC)
    Specificité
    FKHR (Ab-319) antibody detects endogenous levels of total FKHR protein.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogène
    The antiserum was produced against synthesized non-phosphopeptide derived from human FKHR around the phosphorylation site of serine 319.
    Top Product
    Discover our top product FOXO1 Anticorps primaire
  • Indications d'application
    WB: 1:500~1:1000
    IHC: 1:50~1:100.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    100ug/100ul.
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Zhao, Gan, Pan, Kan, Majeski, Adam, Unterman: "Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms." dans: The Biochemical journal, Vol. 378, Issue Pt 3, pp. 839-49, (2004) (PubMed).

    Rena, Woods, Prescott, Peggie, Unterman, Williams, Cohen: "Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion." dans: The EMBO journal, Vol. 21, Issue 9, pp. 2263-71, (2002) (PubMed).

    Rena, Prescott, Guo, Cohen, Unterman: "Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting." dans: The Biochemical journal, Vol. 354, Issue Pt 3, pp. 605-12, (2001) (PubMed).

    Guo, Rena, Cichy, He, Cohen, Unterman: "Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence." dans: The Journal of biological chemistry, Vol. 274, Issue 24, pp. 17184-92, (1999) (PubMed).

  • Antigène
    FOXO1 (Forkhead Box O1 (FOXO1))
    Autre désignation
    FKHR (FOXO1 Produits)
    Synonymes
    anticorps FKH1, anticorps FKHR, anticorps FOXO1A, anticorps FoxO1a.1, anticorps foxo1, anticorps zgc:153388, anticorps Fkhr, anticorps Foxo1a, anticorps AI876417, anticorps Afxh, anticorps Fkhr1, anticorps fkh1, anticorps fkhr, anticorps foxo1a, anticorps xFoxO1, anticorps FoxO1A, anticorps foxo1a.2, anticorps forkhead box O1, anticorps forkhead box O1 a, anticorps forkhead box O1 L homeolog, anticorps forkhead box O1 b, anticorps FOXO1, anticorps foxo1a, anticorps Foxo1, anticorps foxo1, anticorps foxo1.L, anticorps foxo1b
    Pathways
    Signalisation PI3K-Akt, Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling
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