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GPC1 anticorps (C-Term)

GPC1 Reactivité: Humain, Souris IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN966218
  • Antigène Voir toutes GPC1 Anticorps
    GPC1 (Glypican 1 (GPC1))
    Épitope
    • 15
    • 15
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 45
    • 19
    • 13
    Humain, Souris
    Hôte
    • 57
    • 8
    • 2
    Lapin
    Clonalité
    • 59
    • 8
    Polyclonal
    Conjugué
    • 26
    • 10
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp GPC1 est non-conjugé
    Application
    • 32
    • 26
    • 26
    • 24
    • 13
    • 8
    • 8
    • 8
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    Immunohistochemistry (IHC)
    Purification
    Purified by antigen-specific affinity chromatography.
    Immunogène
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human GPC1(Glypican-1 precursor)
    Top Product
    Discover our top product GPC1 Anticorps primaire
  • Indications d'application
    ELISA, Western blotting: 1µg/ml for 2hrs.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    This antibody is stored in PBS, 50% glycerol
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Davies, Blackhall, Shanks, David, McGown, Swindell, Slade, Martin-Hirsch, Gallagher, Jayson: "Distribution and clinical significance of heparan sulfate proteoglycans in ovarian cancer." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 10, Issue 15, pp. 5178-86, (2004) (PubMed).

  • Antigène
    GPC1 (Glypican 1 (GPC1))
    Autre désignation
    GPC1 (GPC1 Produits)
    Synonymes
    anticorps gpc1, anticorps zgc:63947, anticorps GPC1, anticorps Glypican-1, anticorps glypican, anticorps AI462976, anticorps HSPG M12, anticorps HSPGM12, anticorps glypican 1b, anticorps glypican 1, anticorps gpc1b, anticorps GPC1, anticorps gpc1, anticorps Gpc1
    Sujet
    GPC1(Glypican-1) is a cell surface proteoglycan that bears heparan sulfate. The protein is attached to the membrane by a GPI-anchor. This cell-associated glypican is further processed to give rise to a medium-released species. The glypican-1 is required for efficient TGF-beta1 signaling in pancreatic cancer cells. The syndecan-1 and glypican-1 have roles in progression of ovarian cancer. Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.
    Pathways
    Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation
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