GSK3 alpha anticorps

N° du produit ABIN966233

Détail du produit anti-GSK3 alpha anticorps

Antigène: GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSK3 alpha est non-conjugé

Application: Immunohistochemistry (IHC)

Specificité: GSK3 (Ab-21) Antibody detects endogenous levels of total GSK3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: This antiserum was produced against synthesized non-phosphopeptide derived from human GSK3 around the phosphorylation site of serine 21 (T-S-SP-F-A).

Information d'application

Indications d'application: WB: 1:500~1:1000
IHC: 1:50~1:100.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-GSK3 alpha (ABIN966233)

Welsh, Wilson, Proud: "GSK3: a SHAGGY frog story." dans: Trends in cell biology, Vol. 6, Issue 7, pp. 274-9, (2004) (PubMed).

Leadbetter: "Cultivation of recalcitrant microbes: cells are alive, well and revealing their secrets in the 21st century laboratory." dans: Current opinion in microbiology, Vol. 6, Issue 3, pp. 274-81, (2003) (PubMed).

Barry, Graham, Fry, Gibbins: "Regulation of glycogen synthase kinase 3 in human platelets: a possible role in platelet function?" dans: FEBS letters, Vol. 553, Issue 1-2, pp. 173-8, (2003) (PubMed).

Koivisto, Alavian, Hakkinen, Pelech, McCulloch, Larjava: "Glycogen synthase kinase-3 regulates formation of long lamellipodia in human keratinocytes." dans: Journal of cell science, Vol. 116, Issue Pt 18, pp. 3749-60, (2003) (PubMed).

Srivastava, Pandey: "Potential mechanism(s) involved in the regulation of glycogen synthesis by insulin." dans: Molecular and cellular biochemistry, Vol. 182, Issue 1-2, pp. 135-41, (1999) (PubMed).

Pandey, Anand-Srivastava, Srivastava: "Vanadyl sulfate-stimulated glycogen synthesis is associated with activation of phosphatidylinositol 3-kinase and is independent of insulin receptor tyrosine phosphorylation." dans: Biochemistry, Vol. 37, Issue 19, pp. 7006-14, (1998) (PubMed).

Cross, Alessi, Cohen, Andjelkovich, Hemmings: "Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B." dans: Nature, Vol. 378, Issue 6559, pp. 785-9, (1996) (PubMed).

Détails sur GSK3 alpha

Antigène: GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))

Autre désignation: GSK3alpha (GSK3a Produits)

Synonymes: anticorps 2700086H06Rik, anticorps GSK3A, anticorps GSK-3[a], anticorps GSK-3[b], anticorps GSK3, anticorps gsk3a, anticorps xgsk3, anticorps glycogen synthase kinase 3 alpha, anticorps glycogen synthase kinase 3 alpha b, anticorps glycogen synthase kinase 3 alpha S homeolog, anticorps GSK3A, anticorps Gsk3a, anticorps gsk3a, anticorps gsk3ab, anticorps gsk3a.S, anticorps Bm1_31380

Pathways: Signalisation PI3K-Akt, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, BCR Signaling, L'effet Warburg