HDAC4 anticorps

N° du produit ABIN966262

Détail du produit anti-HDAC4 anticorps

Antigène: HDAC4 (Histone Deacetylase 4 (HDAC4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HDAC4 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human HDAC4 expressed in E. Coli.

Clone: 7B2

Isotype: IgG1

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-HDAC4 (ABIN966262)

Ficner: "Novel structural insights into class I and II histone deacetylases." dans: Current topics in medicinal chemistry, Vol. 9, Issue 3, pp. 235-40, (2009) (PubMed).

Nishino, Miyazaki, Hoshino, Miwa, Horinouchi, Yoshida: "14-3-3 regulates the nuclear import of class IIa histone deacetylases." dans: Biochemical and biophysical research communications, Vol. 377, Issue 3, pp. 852-6, (2008) (PubMed).

Détails sur HDAC4

Antigène: HDAC4 (Histone Deacetylase 4 (HDAC4))

Autre désignation: HDAC4 (HDAC4 Produits)

Synonymes: anticorps CG1770, anticorps DHDAC4, anticorps Dmel\\CG1770, anticorps GC1770, anticorps HDAC, anticorps HDAC4a, anticorps dHDAC4, anticorps dmHDA405, anticorps hdac4, anticorps dana_GLEANR_19966, anticorps DanaGF18710, anticorps GF18710, anticorps HDAC4, anticorps AHO3, anticorps BDMR, anticorps HA6116, anticorps HD4, anticorps HDAC-4, anticorps HDAC-A, anticorps HDACA, anticorps 4932408F19Rik, anticorps AI047285, anticorps wu:fa96d08, anticorps wu:fc56f08, anticorps zgc:152701, anticorps histone deacetylase 4, anticorps hypothetical protein, anticorps Histone deacetylase 4, anticorps GF18710 gene product from transcript GF18710-RC, anticorps PTRG_03699, anticorps PGTG_15512, anticorps HDAC4, anticorps Dana\GF18710, anticorps Hdac4, anticorps hdac4

Sujet: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Synonyms: HD4, HDACA, HA6116, HDAC-A, KIAA0288, HDAC4

Poids moléculaire: 119kDa

ID gène: 9759

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process