HGF anticorps (N-Term)

N° du produit ABIN966282

Détail du produit anti-HGF anticorps

Antigène: HGF (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HGF est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Réactivité croisée: Souris, Rat (Rattus)

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Hepatocyte growth factor ( HGF) detection. Tested with WB, IHC-P, IHC-F, ICC in Human, Mouse, Rat.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminal of human HGF, different from the related mouse sequence by two amino acids.< br/>Immunogen was affinity purified.

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.

Références pour anticorps anti-HGF (ABIN966282)

Kilby, Afford, Li, Strain, Ahmed, Whittle: "Localisation of hepatocyte growth factor and its receptor (c-met) protein and mRNA in human term placenta." dans: Growth factors (Chur, Switzerland), Vol. 13, Issue 1-2, pp. 133-9, (1996) (PubMed).

Tamura, Arakaki, Tsubouchi, Takada, Daikuhara: "Enhancement of human hepatocyte growth factor production by interleukin-1 alpha and -1 beta and tumor necrosis factor-alpha by fibroblasts in culture." dans: The Journal of biological chemistry, Vol. 268, Issue 11, pp. 8140-5, (1993) (PubMed).

Gohda, Tsubouchi, Nakayama, Hirono, Sakiyama, Takahashi, Miyazaki, Hashimoto, Daikuhara: "Purification and partial characterization of hepatocyte growth factor from plasma of a patient with fulminant hepatic failure." dans: The Journal of clinical investigation, Vol. 81, Issue 2, pp. 414-9, (1988) (PubMed).

Détails sur HGF

Antigène: HGF (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))

Autre désignation: Hepatocyte growth factor (HGF Produits)

Synonymes: anticorps DFNB39, anticorps F-TCF, anticorps HGFB, anticorps HPTA, anticorps SF, anticorps HGF, anticorps C230052L06Rik, anticorps HGF/SF, anticorps NK1, anticorps NK2, anticorps SF/HGF, anticorps hepatocyte growth factor, anticorps HGF, anticorps Hgf

Sujet: Hepatocyte Growth Factor (HGF) is structurally similar, but not identical to scatter factor, a molecule shown to stimulate the dissociation and scattering of epithelial cells. It mapped to 7q21. 1 and involved in liver regeneration. Human HGF has been purified approximately 209,000-fold with 18 % yield from plasma of a patient with fulminant hepatic failure. It consists of 2 chains, heavy and light with molecular weights of 54,000-65,000 and 31,500-34,500, respectively. HGF is a potent mitogen, morphogen and motogen to both endothelial and epithelial cell types and is linked to a tyrosine kinase, proto-oncogene, c-met receptor. It indicated that HGF may serve as a paracrine mediator to control placental development and growth.

Pathways: Signalisation RTK, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor