NFKBIA anticorps

N° du produit ABIN966365

Détail du produit anti-NFKBIA anticorps

Antigène: NFKBIA (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFKBIA est non-conjugé

Application: Immunohistochemistry (IHC)

Specificité: IB- (Ab-32/36) antibody detects endogenous levels of total IB- protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized non-phosphopeptide derived from human IB- around the phosphorylation site of serine 32/36 (H-D-SP-G-L- D-SP -M-K).

Information d'application

Indications d'application: WB: 1:500~1:1000
IHC: 1:50~1:100.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-NFKBIA (ABIN966365)

Mattioli, Sebald, Bucher, Charles, Nakano, Doi, Kracht, Schmitz: "Transient and selective NF-kappa B p65 serine 536 phosphorylation induced by T cell costimulation is mediated by I kappa B kinase beta and controls the kinetics of p65 nuclear import." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 10, pp. 6336-44, (2004) (PubMed).

Courtois, Smahi, Reichenbach, Döffinger, Cancrini, Bonnet, Puel, Chable-Bessia, Yamaoka, Feinberg, Dupuis-Girod, Bodemer, Livadiotti, Novelli, Rossi, Fischer, Israël, Munnich, Le Deist, Casanova: "A hypermorphic IkappaBalpha mutation is associated with autosomal dominant anhidrotic ectodermal dysplasia and T cell immunodeficiency." dans: The Journal of clinical investigation, Vol. 112, Issue 7, pp. 1108-15, (2003) (PubMed).

Nair, Venkatraman, Maliekal, Nair, Karunagaran: "NF-kappaB is constitutively activated in high-grade squamous intraepithelial lesions and squamous cell carcinomas of the human uterine cervix." dans: Oncogene, Vol. 22, Issue 1, pp. 50-8, (2003) (PubMed).

Fan, Yang, Engelhardt: "Temporal pattern of NFkappaB activation influences apoptotic cell fate in a stimuli-dependent fashion." dans: Journal of cell science, Vol. 115, Issue Pt 24, pp. 4843-53, (2002) (PubMed).

Schubert, Neeman, Resnick: "A novel mechanism for the inhibition of NF-kappaB activation in vascular endothelial cells by natural antioxidants." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 16, Issue 14, pp. 1931-3, (2002) (PubMed).

Détails sur NFKBIA

Antigène: NFKBIA (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))

Autre désignation: IkB-alpha (NFKBIA Produits)

Synonymes: anticorps IKBA, anticorps MAD-3, anticorps NFKBI, anticorps AI462015, anticorps Nfkbi, anticorps RL/IF-1, anticorps ECI-6/IKBA, anticorps NFKBIA, anticorps ikbaB, anticorps wu:fb81f08, anticorps zgc:56666, anticorps zgc:77616, anticorps ikbaA, anticorps wu:fj16a07, anticorps zgc:85769, anticorps NFKB inhibitor alpha, anticorps nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha, anticorps nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b, anticorps nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a, anticorps NFKBIA, anticorps Nfkbia, anticorps nfkbiab, anticorps nfkbiaa

Pathways: Signalisation NF-kappaB, TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Maintenance of Protein Location, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, BCR Signaling