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IKBKB anticorps (C-Term)

IKBKB Reactivité: Humain IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN966372
  • Antigène Voir toutes IKBKB Anticorps
    IKBKB (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))
    Épitope
    • 29
    • 29
    • 16
    • 16
    • 16
    • 15
    • 9
    • 9
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 284
    • 113
    • 72
    • 8
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Humain
    Hôte
    • 289
    • 20
    • 1
    Lapin
    Clonalité
    • 285
    • 25
    Polyclonal
    Conjugué
    • 133
    • 24
    • 24
    • 23
    • 18
    • 16
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    Cet anticorp IKBKB est non-conjugé
    Application
    • 160
    • 118
    • 107
    • 80
    • 80
    • 31
    • 29
    • 25
    • 22
    • 20
    • 15
    • 10
    • 4
    • 3
    • 1
    • 1
    Immunohistochemistry (IHC)
    Immunogène
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to very C-terminal residues of human IKBKB (Inhibitor of nuclear factor kappa-B kinase subunit beta)
    Top Product
    Discover our top product IKBKB Anticorps primaire
  • Restrictions
    For Research Use only
  • Stock
    4 °C
  • Hu, Wang: "IkappaB kinase-alpha and -beta genes are coexpressed in adult and embryonic tissues but localized to different human chromosomes." dans: Gene, Vol. 222, Issue 1, pp. 31-40, (1999) (PubMed).

    Sanz, Sanchez, Lallena, Diaz-Meco, Moscat: "The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation." dans: The EMBO journal, Vol. 18, Issue 11, pp. 3044-53, (1999) (PubMed).

    Shindo, Nakano, Sakon, Yagita, Mihara, Okumura: "Assignment of IkappaB kinase beta (IKBKB) to human chromosome band 8p12-->p11 by in situ hybridization." dans: Cytogenetics and cell genetics, Vol. 82, Issue 1-2, pp. 32-3, (1998) (PubMed).

    Nemoto, DiDonato, Lin: "Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase." dans: Molecular and cellular biology, Vol. 18, Issue 12, pp. 7336-43, (1998) (PubMed).

    Cohen, Henzel, Baeuerle: "IKAP is a scaffold protein of the IkappaB kinase complex." dans: Nature, Vol. 395, Issue 6699, pp. 292-6, (1998) (PubMed).

  • Antigène
    IKBKB (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))
    Autre désignation
    IKBKB (IKBKB Produits)
    Synonymes
    anticorps ikk-beta, anticorps ikk2, anticorps ikkb, anticorps ikkbeta, anticorps IKBKB, anticorps IKKB, anticorps CG4201, anticorps DIK, anticorps DLAK, anticorps DmIKK, anticorps DmIKKBeta, anticorps DmIKKb, anticorps DmIKKbeta, anticorps DmIkkbeta, anticorps Dmel\\CG4201, anticorps Dmikkb, anticorps Dmikkbeta, anticorps IK, anticorps IKK, anticorps IKK-beta, anticorps IKKb, anticorps IKKbeta, anticorps IRD-5, anticorps IRD5, anticorps Ik, anticorps Ikkb, anticorps Ikkbeta, anticorps Ird-5, anticorps Ird5, anticorps LRK, anticorps Lak, anticorps anon-89Bd, anticorps dIKK, anticorps dIKK-beta, anticorps dIKKbeta, anticorps dLak, anticorps dmIKKbeta, anticorps ikk, anticorps ird, anticorps ird5/DmIkk[beta], anticorps IKK2, anticorps NFKBIKB, anticorps AIM-1, anticorps AI132552, anticorps IKK-2, anticorps IKK[b], anticorps inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta L homeolog, anticorps inhibitor of nuclear factor kappa B kinase subunit beta, anticorps I-kappaB kinase beta, anticorps inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, anticorps inhibitor of kappaB kinase beta, anticorps ikbkb.L, anticorps IKBKB, anticorps ikbkb, anticorps IKKbeta, anticorps Ikbkb
    Sujet
    IKBKB (Inhibitor of nuclear factor kappa-B kinase subunit beta) acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. IKBKB also phosphorylates NCOA3. Component of the I-kappa-B-kinase (IKK) core complex consists of CHUK, IKBKB and IKBKG, probably four alpha/CHUK-beta/IKBKB dimers are associated with four gamma/IKBKG subunits. The IKK core complex seems to associate with regulatory or adapter proteins to form a IKK-signalosome holo-complex. Part of a complex composed of NCOA2, NCOA3, CHUK/IKKA, IKBKB, IKBKG and CREBBP. Part of a 70-90 kDa complex at least consisting of CHUK/IKKA, IKBKB, NFKBIA, RELA, IKBKAP and MAP3K14.
    Synonyms: IKKB
    Pathways
    Signalisation NF-kappaB, Signalisation RTK, TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
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