JAK2 anticorps
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- Antigène Voir toutes JAK2 Anticorps
- JAK2 (Janus Kinase 2 (JAK2))
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp JAK2 est non-conjugé
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Application
- Immunohistochemistry (IHC)
- Specificité
- JAK2 (Ab-221) antibody detects endogenous levels of total JAK2 protein.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogène
- The antiserum was produced against synthesized non-phosphopeptide derived from human JAK2 around the phosphorylation site of tyrosine 221 (Q-D-YP-H-I).
- Top Product
- Discover our top product JAK2 Anticorps primaire
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- Indications d'application
- IHC: 1:50-1:100.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100ug/100ul.
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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Tyrosine phosphorylation of Jak2 in the JH2 domain inhibits cytokine signaling." dans: Molecular and cellular biology, Vol. 24, Issue 11, pp. 4968-78, (2004) (PubMed).
: "Autophosphorylation of JAK2 on tyrosines 221 and 570 regulates its activity." dans: Molecular and cellular biology, Vol. 24, Issue 11, pp. 4955-67, (2004) (PubMed).
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Tyrosine phosphorylation of Jak2 in the JH2 domain inhibits cytokine signaling." dans: Molecular and cellular biology, Vol. 24, Issue 11, pp. 4968-78, (2004) (PubMed).
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- Antigène
- JAK2 (Janus Kinase 2 (JAK2))
- Autre désignation
- JAK2 (JAK2 Produits)
- Synonymes
- anticorps JAK2bCA, anticorps jak2, anticorps JTK10, anticorps THCYT3, anticorps AI504024, anticorps C81284, anticorps Fd17, anticorps JAK-2, anticorps Janus kinase 2b, anticorps Janus kinase 2, anticorps jak2b, anticorps JAK2, anticorps Jak2
- Pathways
- Signalistation JAK/STAT, Signalisation RTK, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
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