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JAK2 anticorps

JAK2 Reactivité: Humain, Rat, Souris IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN966432
  • Antigène Voir toutes JAK2 Anticorps
    JAK2 (Janus Kinase 2 (JAK2))
    Reactivité
    • 177
    • 101
    • 97
    • 18
    • 18
    • 3
    • 2
    • 2
    • 1
    Humain, Rat, Souris
    Hôte
    • 179
    • 6
    • 2
    Lapin
    Clonalité
    • 164
    • 23
    Polyclonal
    Conjugué
    • 92
    • 16
    • 10
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    Cet anticorp JAK2 est non-conjugé
    Application
    • 135
    • 86
    • 62
    • 61
    • 29
    • 27
    • 26
    • 25
    • 17
    • 12
    • 10
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Specificité
    JAK2 (Ab-221) antibody detects endogenous levels of total JAK2 protein.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogène
    The antiserum was produced against synthesized non-phosphopeptide derived from human JAK2 around the phosphorylation site of tyrosine 221 (Q-D-YP-H-I).
    Top Product
    Discover our top product JAK2 Anticorps primaire
  • Indications d'application
    IHC: 1:50-1:100.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    100ug/100ul.
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Feener, Rosario, Dunn, Stancheva, Myers: "Tyrosine phosphorylation of Jak2 in the JH2 domain inhibits cytokine signaling." dans: Molecular and cellular biology, Vol. 24, Issue 11, pp. 4968-78, (2004) (PubMed).

    Argetsinger, Kouadio, Steen, Stensballe, Jensen, Carter-Su: "Autophosphorylation of JAK2 on tyrosines 221 and 570 regulates its activity." dans: Molecular and cellular biology, Vol. 24, Issue 11, pp. 4955-67, (2004) (PubMed).

  • Antigène
    JAK2 (Janus Kinase 2 (JAK2))
    Autre désignation
    JAK2 (JAK2 Produits)
    Synonymes
    anticorps JAK2bCA, anticorps jak2, anticorps JTK10, anticorps THCYT3, anticorps AI504024, anticorps C81284, anticorps Fd17, anticorps JAK-2, anticorps Janus kinase 2b, anticorps Janus kinase 2, anticorps jak2b, anticorps JAK2, anticorps Jak2
    Pathways
    Signalistation JAK/STAT, Signalisation RTK, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
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