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LKB1 anticorps (C-Term)

STK11 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN966488
  • Antigène Voir toutes LKB1 (STK11) Anticorps
    LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
    Épitope
    • 27
    • 23
    • 20
    • 19
    • 16
    • 15
    • 15
    • 8
    • 7
    • 7
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    • 6
    • 6
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    • 2
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    • 2
    • 2
    • 2
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    • 2
    • 1
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    • 1
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    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    C-Term
    Reactivité
    • 183
    • 115
    • 63
    • 16
    • 15
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 188
    • 9
    Lapin
    Clonalité
    • 191
    • 6
    Polyclonal
    Conjugué
    • 81
    • 13
    • 11
    • 11
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    Cet anticorp LKB1 est non-conjugé
    Application
    • 151
    • 84
    • 65
    • 65
    • 38
    • 28
    • 21
    • 15
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Souris, Rat (Rattus)
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase STK11 (STK11) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
    Immunogène
    A synthetic peptide corresponding to a sequence at the C-terminal of human STK11, different from the mouse sequence by one amino acid.< br/>Immunogen was affinity purified.
    Isotype
    IgG
    Top Product
    Discover our top product STK11 Anticorps primaire
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Agent conservateur
    Sodium azide, Thimerosal (Merthiolate)
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.
  • Jenne, Reimann, Nezu, Friedel, Loff, Jeschke, Müller, Back, Zimmer: "Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase." dans: Nature genetics, Vol. 18, Issue 1, pp. 38-43, (1998) (PubMed).

  • Antigène
    LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
    Autre désignation
    Serine/threonine-protein kinase STK11 (STK11 Produits)
    Synonymes
    anticorps pjs, anticorps LKB1, anticorps XEEK1, anticorps Stk11, anticorps PJS, anticorps hLKB1, anticorps AA408040, anticorps Lkb1, anticorps Par-4, anticorps R75140, anticorps mLKB1, anticorps wu:fj61a05, anticorps zgc:110180, anticorps xeek1, anticorps serine/threonine kinase 11, anticorps polarization-related protein LKB1, anticorps serine/threonine kinase 11 L homeolog, anticorps STK11, anticorps stk11, anticorps LOC662493, anticorps Stk11, anticorps stk11.L
    Sujet
    Serine/threonine kinase 11 or LKB1 is a protein kinase which in humans is encoded by the STK11 gene. The STK11/LKB1 gene, which encodes a member of the serine/threonine kinase, regulates cell polarity and functions as a tumour suppressor Smith et al. (1999) found that the mouse Lkb1 gene encodes a protein showing strong sequence similarity to human LKB1. Karuman et al. (2001) demonstrated that LKB1 physically associates with p53 (191170) and regulates specific p53-dependent apoptosis pathways. Jenne et al. (1998) determined that the STK11 gene extends over 23 kb of genomic DNA and is composed of 9 exons, which are transcribed in telomere-to-centromere direction. Smith et al. (1999) found that the mouse Lkb1 gene consists of 10 exons covering approximately 15 kb.
    Pathways
    AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg
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