LSD1 anticorps

N° du produit ABIN966497

Détail du produit anti-LSD1 anticorps

Antigène: LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

Reactivité: Humain

Hôte: Veuillez nous consulter SVP

Clonalité: Monoclonal

Conjugué: Cet anticorp LSD1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: Ni-NTA purified truncated recombinant human LSD1 expressed in E. Coli strain BL21 (DE3)

Purification: Crude Asites are purified by protein A affinity chromatography.

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
IHC(F): 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Stock: -20 °C

Références pour anticorps anti-LSD1 (ABIN966497)

Metzger, Wissmann, Yin, Müller, Schneider, Peters, Günther, Buettner, Schüle: "LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription." dans: Nature, Vol. 437, Issue 7057, pp. 436-9, (2005) (PubMed).

Détails sur LSD1

Antigène: LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

Autre désignation: LSD1/AOF2 (KDM1A Produits)

Synonymes: anticorps AOF2, anticorps BHC110, anticorps KDM1, anticorps LSD1, anticorps 1810043O07Rik, anticorps AA408884, anticorps Aof2, anticorps D4Ertd478e, anticorps Kdm1, anticorps Lsd1, anticorps mKIAA0601, anticorps DKFZp459N2450, anticorps RGD1562975, anticorps aof2, anticorps kdm1, anticorps wu:fb82e06, anticorps wu:fc51a02, anticorps wu:fj36a05, anticorps wu:fj66b06, anticorps KDM1A, anticorps lsd1, anticorps xLSD1, anticorps AtLSD1, anticorps F9F13.30, anticorps F9F13_30, anticorps LESION SIMULATING DISEASE, anticorps LESION SIMULATING DISEASE 1, anticorps lysine demethylase 1A, anticorps lysine (K)-specific demethylase 1A, anticorps lysine (K)-specific demethylase 1a, anticorps LSD1 zinc finger family protein, anticorps KDM1A, anticorps Kdm1a, anticorps kdm1a, anticorps LSD1

Sujet: The amine oxidase domain 2(AOF2)gene encodes a nuclear protein(LSD1,~95kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex(es) on chromatin.

ID gène: 23028

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, L'effet Warburg