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MAPK11 anticorps

MAPK11 Reactivité: Humain, Souris IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN966523
  • Antigène Voir toutes MAPK11 Anticorps
    MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))
    Reactivité
    • 66
    • 33
    • 22
    • 2
    • 1
    • 1
    Humain, Souris
    Hôte
    • 81
    • 4
    • 3
    Lapin
    Clonalité
    • 83
    • 5
    Polyclonal
    Conjugué
    • 38
    • 9
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp MAPK11 est non-conjugé
    Application
    • 82
    • 44
    • 29
    • 26
    • 26
    • 11
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Immunogène
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to middle amino acid residues of human MAPK11 (Mitogen-activated protein kinase 11)
    Top Product
    Discover our top product MAPK11 Anticorps primaire
  • Restrictions
    For Research Use only
  • Stock
    4 °C
  • Kumar, McDonnell, Gum, Hand, Lee, Young: "Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles." dans: Biochemical and biophysical research communications, Vol. 235, Issue 3, pp. 533-8, (1997) (PubMed).

    Stein, Yang, Young, Janknecht, Hunter, Murray, Barbosa: "p38-2, a novel mitogen-activated protein kinase with distinct properties." dans: The Journal of biological chemistry, Vol. 272, Issue 31, pp. 19509-17, (1997) (PubMed).

    Jiang, Chen, Li, Guo, Gegner, Lin, Han: "Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)." dans: The Journal of biological chemistry, Vol. 271, Issue 30, pp. 17920-6, (1996) (PubMed).

  • Antigène
    MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))
    Autre désignation
    MAPK11 (MAPK11 Produits)
    Synonymes
    anticorps ATMPK11, anticorps F22L4.10, anticorps F22L4_10, anticorps MAP kinase 11, anticorps zgc:86905, anticorps P38B, anticorps P38BETA2, anticorps PRKM11, anticorps SAPK2, anticorps SAPK2B, anticorps p38-2, anticorps p38Beta, anticorps P38b, anticorps Prkm11, anticorps Sapk2, anticorps Sapk2b, anticorps p38beta, anticorps p38beta2, anticorps p38b, anticorps sapk2, anticorps prkm11, anticorps sapk2b, anticorps mitogen-activated protein kinase 11, anticorps MAP kinase 11, anticorps mapk11, anticorps LOC9328118, anticorps MPK11, anticorps MAPK11, anticorps Mapk11, anticorps PTRG_02565
    Sujet
    MAPK11 (Mitogen-activated protein kinase 11) is involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment, by cytokines, or by environmental stress. MAPK11 (Mitogen-activated protein kinase 11) phosphorylates preferentially transcription factor ATF2. MAPK11 (Mitogen-activated protein kinase 11) is activated by phosphorylation on threonine and tyrosine by MKK6. MAPK11 is inhibited by pyridinyl-imidazole related compounds. Highest levels of MAPK11 expression is in the brain and heart. MAPK11 is also expressed in the placenta, lung, liver, skeletal muscle, kidney and pancreas. The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases. MAPK11 is dually phosphorylated on Thr-180 and Tyr-182, which activates the enzyme. MAPK11 belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family and MAP kinase subfamily. MAPK11 contains 1 protein kinase domain.
    Synonyms: PRKM11, SAPK2 (Stress-activated protein kinase 2), p38-2 (Mitogen-activated protein kinase p38 beta), p38b (MAP kinase p38 beta)
    Pathways
    Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Response to Water Deprivation, Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Hepatitis C, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins
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