P90RSK (Ab-352) antibody detects endogenous levels of total p90RSK protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogène
The antiserum was produced against synthesized non-phosphopeptide derived from mouse p90RSK around the phosphorylation site of serine 352 (R-D-SP-P-G).
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Itoh, Ding, Bains, Wang, Takeishi, Jalili, King, Walsh, Yan, Abe: "Role of p90 ribosomal S6 kinase (p90RSK) in reactive oxygen species and protein kinase C beta (PKC-beta)-mediated cardiac troponin I phosphorylation." dans: The Journal of biological chemistry, Vol. 280, Issue 25, pp. 24135-42, (2005) (PubMed).
Silverman, Frödin, Gammeltoft, Maller: "Activation of p90 Rsk1 is sufficient for differentiation of PC12 cells." dans: Molecular and cellular biology, Vol. 24, Issue 24, pp. 10573-83, (2004) (PubMed).
Eisenmann, VanBrocklin, Staffend, Kitchen, Koo: "Mitogen-activated protein kinase pathway-dependent tumor-specific survival signaling in melanoma cells through inactivation of the proapoptotic protein bad." dans: Cancer research, Vol. 63, Issue 23, pp. 8330-7, (2003) (PubMed).
Antigène
RPS6KA3
(Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))