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PAX8 anticorps

PAX8 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 2D4 unconjugated
N° du produit ABIN966806
  • Antigène Voir toutes PAX8 Anticorps
    PAX8 (Paired Box 8 (PAX8))
    Reactivité
    • 112
    • 48
    • 45
    • 20
    • 20
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 73
    • 38
    • 1
    Souris
    Clonalité
    • 56
    • 56
    Monoclonal
    Conjugué
    • 63
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PAX8 est non-conjugé
    Application
    • 88
    • 36
    • 31
    • 31
    • 26
    • 17
    • 16
    • 12
    • 11
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Ascitic fluid
    Immunogène
    Purified recombinant fragment of human PAX8 expressed in E. Coli.
    Clone
    2D4
    Isotype
    IgG1
    Top Product
    Discover our top product PAX8 Anticorps primaire
  • Indications d'application
    Western Bloting: 1/500 - 1/2000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
  • McKnight, Cohen, Siddiqui: "Utility of paired box gene 8 (PAX8) expression in fluid and fine-needle aspiration cytology: an immunohistochemical study of metastatic ovarian serous carcinoma." dans: Cancer cytopathology, Vol. 118, Issue 5, pp. 298-302, (2010) (PubMed).

    Chia, Sharifah, Reena, Zubaidah, Clarence-Ko, Rohaizak, Naqiyah, Srijit, Hisham, Asmiati, Rafie: "Fluorescence in situ hybridization analysis using PAX8- and PPARG-specific probes reveals the presence of PAX8-PPARG translocation and 3p25 aneusomy in follicular thyroid neoplasms." dans: Cancer genetics and cytogenetics, Vol. 196, Issue 1, pp. 7-13, (2009) (PubMed).

  • Antigène
    PAX8 (Paired Box 8 (PAX8))
    Autre désignation
    PAX8 (PAX8 Produits)
    Synonymes
    anticorps PAX8, anticorps XPax-8, anticorps XPax8, anticorps pax-8, anticorps PAX-8, anticorps Pax-8, anticorps paired box 8, anticorps paired box 8 L homeolog, anticorps PAX8, anticorps pax8, anticorps Pax8, anticorps pax8.L
    Sujet
    This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas.
    Tissue specificity: Expressed in the excretory system, thyroid gland and Wilms tumors.ABCAM: This protein is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain, an octapeptide, and a paired-type homeodomain. This family plays critical roles during fetal development and cancer growth. The specific function of the PAX8 is unknown but it may involve kidney cell differentiation, thyroid development, or thyroid dysgenesis. Alternative splicing in the gene by inclusion or exclusion of exons 7 and/or 8 has produced several known products but the biological significance of the variants is unknown. Several other splice variants have been proposed but the full nature of these products has not been described. Pax8 is also a marker of otic progenitor cells.
    Synonyms: PAX8
    Poids moléculaire
    60kDa
    ID gène
    7846
    Pathways
    Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation
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