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PLK1 anticorps

PLK1 Reactivité: Humain, Souris, Rat IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN966866
  • Antigène Voir toutes PLK1 Anticorps
    PLK1 (Polo-Like Kinase 1 (PLK1))
    Reactivité
    • 142
    • 53
    • 45
    • 8
    • 8
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 116
    • 25
    • 2
    • 1
    Lapin
    Clonalité
    • 112
    • 32
    Polyclonal
    Conjugué
    • 83
    • 7
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp PLK1 est non-conjugé
    Application
    • 111
    • 53
    • 36
    • 28
    • 27
    • 20
    • 19
    • 16
    • 10
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Immunogène
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-residues of human PLK1(Serine/threonine-protein kinase PLK1) (Polo-like kinase 1)
    Top Product
    Discover our top product PLK1 Anticorps primaire
  • Restrictions
    For Research Use only
  • Stock
    4 °C
  • Jang, Ma, Terada, Erikson: "Phosphorylation of threonine 210 and the role of serine 137 in the regulation of mammalian polo-like kinase." dans: The Journal of biological chemistry, Vol. 277, Issue 46, pp. 44115-20, (2002) (PubMed).

    Wind, Kelm, Nigg, Lehmann: "Identification of phosphorylation sites in the polo-like kinases Plx1 and Plk1 by a novel strategy based on element and electrospray high resolution mass spectrometry." dans: Proteomics, Vol. 2, Issue 11, pp. 1516-23, (2002) (PubMed).

    Uchiumi, Longo, Ferris: "Cell cycle regulation of the human polo-like kinase (PLK) promoter." dans: The Journal of biological chemistry, Vol. 272, Issue 14, pp. 9166-74, (1997) (PubMed).

    Lee, Erikson: "Plk is a functional homolog of Saccharomyces cerevisiae Cdc5, and elevated Plk activity induces multiple septation structures." dans: Molecular and cellular biology, Vol. 17, Issue 6, pp. 3408-17, (1997) (PubMed).

    Bräuninger, Strebhardt, Rübsamen-Waigmann: "Identification and functional characterization of the human and murine polo-like kinase (Plk) promoter." dans: Oncogene, Vol. 11, Issue 9, pp. 1793-800, (1995) (PubMed).

    Golsteyn, Schultz, Bartek, Ziemiecki, Ried, Nigg: "Cell cycle analysis and chromosomal localization of human Plk1, a putative homologue of the mitotic kinases Drosophila polo and Saccharomyces cerevisiae Cdc5." dans: Journal of cell science, Vol. 107 ( Pt 6), pp. 1509-17, (1994) (PubMed).

  • Antigène
    PLK1 (Polo-Like Kinase 1 (PLK1))
    Autre désignation
    PLK1 (PLK1 Produits)
    Synonymes
    anticorps PLK, anticorps STPK13, anticorps plk, anticorps PLK-1, anticorps Plx1, anticorps stpk13, anticorps Plk, anticorps cb525, anticorps cb636, anticorps ik:tdsubc_2d1, anticorps wu:fb37g11, anticorps wu:fb76g03, anticorps xx:tdsubc_2d1, anticorps polo like kinase 1, anticorps polo like kinase 1 S homeolog, anticorps polo-like kinase 1, anticorps polo-like kinase 1 (Drosophila), anticorps Serine/threonine-protein kinase plk-1, anticorps PLK1, anticorps plk1.S, anticorps plk1, anticorps Plk1, anticorps plk-1
    Sujet
    PLK1(Serine/threonine-protein kinase) that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of APC/C inhibitors, and the regulation of mitotic exit and cytokinesis. PLK1 is activated by serine and threonine phosphorylation. PLK1 interacts with CEP170 and EVI5. PLK1 interacts and phosphorylates ERCC6L. PLK1 accumulates to a maximum during the G2 and M phases, declines to a nearly undetectable level following mitosis and throughout G1 phase, and then begins to accumulate again during S phase. Autophosphorylation and phosphorylation of Ser-137 are not significant events during activation of PLK1 in M phase.
    Synonyms: PLK
    Pathways
    Cycle Cellulaire, M Phase
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