POLRMT anticorps (C-Term)

N° du produit ABIN966880

Détail du produit anti-POLRMT anticorps

Antigène: POLRMT (Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLRMT est non-conjugé

Application: Immunohistochemistry (IHC)

Immunogène: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human POLRMT(DNA-directed RNA polymerase, mitochondrial)

Information d'application

Restrictions: For Research Use only

Stockage

Stock: 4 °C

Références pour anticorps anti-POLRMT (ABIN966880)

Bogenhagen, Rousseau, Burke: "The layered structure of human mitochondrial DNA nucleoids." dans: The Journal of biological chemistry, Vol. 283, Issue 6, pp. 3665-75, (2008) (PubMed).

Kravchenko, Rogozin, Koonin, Chumakov: "Transcription of mammalian messenger RNAs by a nuclear RNA polymerase of mitochondrial origin." dans: Nature, Vol. 436, Issue 7051, pp. 735-9, (2005) (PubMed).

Gaspari, Falkenberg, Larsson, Gustafsson: "The mitochondrial RNA polymerase contributes critically to promoter specificity in mammalian cells." dans: The EMBO journal, Vol. 23, Issue 23, pp. 4606-14, (2004) (PubMed).

Tiranti, Savoia, Forti, DApolito, Centra, Rocchi, Zeviani: "Identification of the gene encoding the human mitochondrial RNA polymerase (h-mtRPOL) by cyberscreening of the Expressed Sequence Tags database." dans: Human molecular genetics, Vol. 6, Issue 4, pp. 615-25, (1997) (PubMed).

Détails sur POLRMT

Antigène: POLRMT (Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT))

Autre désignation: POLRMT (POLRMT Produits)

Sujet: POLRMT(DNA-directed RNA polymerase, mitochondrial) is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNAdirected RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes. POLRMT(DNA-directed RNA polymerase, mitochondrial) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. POLRMT interacts with TFB1M and TFB2M, leading to the stimulation of family.