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Retinoblastoma 1 anticorps

RB1 Reactivité: Humain IHC, ELISA Hôte: Souris Monoclonal 7E4B8 unconjugated
N° du produit ABIN966949
  • Antigène Voir toutes Retinoblastoma 1 (RB1) Anticorps
    Retinoblastoma 1 (RB1)
    Reactivité
    • 300
    • 120
    • 101
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 251
    • 52
    Souris
    Clonalité
    • 238
    • 65
    Monoclonal
    Conjugué
    • 152
    • 19
    • 17
    • 16
    • 11
    • 11
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Retinoblastoma 1 est non-conjugé
    Application
    • 226
    • 132
    • 113
    • 80
    • 79
    • 42
    • 42
    • 36
    • 28
    • 20
    • 19
    • 9
    • 8
    • 6
    • 6
    • 6
    • 4
    • 2
    • 1
    Immunohistochemistry (IHC), ELISA
    Purification
    Ascitic fluid
    Immunogène
    Purified recombinant fragment of human RB expressed in E. Coli.
    Clone
    7E4B8
    Isotype
    IgG1
    Top Product
    Discover our top product RB1 Anticorps primaire
  • Indications d'application
    Immunohistochemistry: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
  • Antigène
    Retinoblastoma 1 (RB1)
    Autre désignation
    RB (RB1 Produits)
    Synonymes
    anticorps OSRC, anticorps RB, anticorps p105-Rb, anticorps pRb, anticorps pp110, anticorps Rb, anticorps Rb-1, anticorps P105-RB, anticorps PP110, anticorps RB11, anticorps zgc:154147, anticorps RB transcriptional corepressor 1, anticorps RB transcriptional corepressor like 1, anticorps retinoblastoma 1, anticorps RB1, anticorps RBL1, anticorps Rb1, anticorps rb1
    Sujet
    The Rb protein regulates differentiation, apoptosis, and cell cycle control by coordinating the cell cycle at G1-S with transcriptional machinery. During G1, cyclin D-dependent kinase-mediated phosphorylation of Rb at Ser-795 marks the conversion of Rb from a transcriptionally repressive, hypophosphorylated state to an inactive, phosphorylated state, which may be sustained through mitosis by differential phosphorylation of up to 16 putative serine or threonine residues. Pediatric cancer retinoblastoma and the formation of other human tumors can be attributed to mutations in the retinoblastoma tumor suppressor gene(Rb).
    Synonyms: RB, pRb, OSRC, pp110, p105-Rb, RB1
    ID gène
    5925
    Pathways
    Cycle Cellulaire, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
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