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SLUG anticorps

SNAI2 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 2H5 unconjugated
N° du produit ABIN967056
  • Antigène Voir toutes SLUG (SNAI2) Anticorps
    SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
    Reactivité
    • 52
    • 20
    • 14
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 40
    • 12
    Souris
    Clonalité
    • 41
    • 10
    Monoclonal
    Conjugué
    • 34
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp SLUG est non-conjugé
    Application
    • 29
    • 20
    • 12
    • 10
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Ascitic fluid
    Immunogène
    Purified recombinant fragment of human SNAI2 expressed in E. Coli.
    Clone
    2H5
    Isotype
    IgG1
    Top Product
    Discover our top product SNAI2 Anticorps primaire
  • Indications d'application
    Western Bloting: 1/500 - 1/2000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
  • Saegusa, Hashimura, Kuwata, Okayasu: "Requirement of the Akt/beta-catenin pathway for uterine carcinosarcoma genesis, modulating E-cadherin expression through the transactivation of slug." dans: The American journal of pathology, Vol. 174, Issue 6, pp. 2107-15, (2009) (PubMed).

    Medici, Hay, Olsen: "Snail and Slug promote epithelial-mesenchymal transition through beta-catenin-T-cell factor-4-dependent expression of transforming growth factor-beta3." dans: Molecular biology of the cell, Vol. 19, Issue 11, pp. 4875-87, (2008) (PubMed).

  • Antigène
    SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
    Autre désignation
    SNAI2 (SNAI2 Produits)
    Synonymes
    anticorps Slug, anticorps Slugh, anticorps Snail2, anticorps snail family transcriptional repressor 2, anticorps snail family zinc finger 2, anticorps Snai2
    Sujet
    This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity.The tumor suppressor protein p53 induces Slug expression in alpha-irradiated cells, Slug protects damaged cells from apoptosis by repressing p53-induced transcription of the proapoptotic Bcl-2 family protein Puma. Mutations in this gene may be associated with sporatic cases of neural tube defects.
    Synonyms: SLUG, WS2D, SLUGH1, MGC10182, SNAI2
    Poids moléculaire
    30kDa
    ID gène
    6591
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