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SLUG anticorps (C-Term)

SNAI2 Reactivité: Humain, Souris, Rat IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN967057
  • Antigène Voir toutes SLUG (SNAI2) Anticorps
    SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
    Épitope
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 51
    • 19
    • 13
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 39
    • 12
    Lapin
    Clonalité
    • 40
    • 10
    Polyclonal
    Conjugué
    • 33
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp SLUG est non-conjugé
    Application
    • 29
    • 20
    • 11
    • 10
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Immunogène
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to near C-terminal residues of human SNAI2
    Top Product
    Discover our top product SNAI2 Anticorps primaire
  • Restrictions
    For Research Use only
  • Stock
    4 °C
  • Larriba, Martín-Villar, García, Pereira, Peña, de Herreros, Bonilla, Muñoz: "Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer." dans: Carcinogenesis, Vol. 30, Issue 8, pp. 1459-68, (2009) (PubMed).

    Wang, Wang, Chang, Wu, Chao, Kao, Yuan, Lin, Yang, Chan, Li, Hong, Yang: "p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug." dans: Nature cell biology, Vol. 11, Issue 6, pp. 694-704, (2009) (PubMed).

    Saegusa, Hashimura, Kuwata, Okayasu: "Requirement of the Akt/beta-catenin pathway for uterine carcinosarcoma genesis, modulating E-cadherin expression through the transactivation of slug." dans: The American journal of pathology, Vol. 174, Issue 6, pp. 2107-15, (2009) (PubMed).

    Hemavathy, Guru, Harris, Chen, Ip: "Human Slug is a repressor that localizes to sites of active transcription." dans: Molecular and cellular biology, Vol. 20, Issue 14, pp. 5087-95, (2000) (PubMed).

    Inukai, Inoue, Kurosawa, Goi, Shinjyo, Ozawa, Mao, Inaba, Look: "SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein." dans: Molecular cell, Vol. 4, Issue 3, pp. 343-52, (1999) (PubMed).

  • Antigène
    SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
    Autre désignation
    SNAI2 (SNAI2 Produits)
    Synonymes
    anticorps Slug, anticorps Slugh, anticorps Snail2, anticorps snail family transcriptional repressor 2, anticorps snail family zinc finger 2, anticorps Snai2
    Sujet
    SNAI2 is a member of the Snail family of C2H2-type zinc finger transcription factors. The SNAI2 protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress Ecadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this SNAI2 gene may be associated with sporatic cases of neural tube defects.
    Synonyms: MGC10182, SLUG, SLUGH1, WS2D
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