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STAT3 anticorps

STAT3 Reactivité: Humain, Souris, Rat IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN967091
  • Antigène Voir toutes STAT3 Anticorps
    STAT3 (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))
    Reactivité
    • 291
    • 150
    • 150
    • 38
    • 27
    • 25
    • 24
    • 19
    • 17
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 228
    • 72
    • 4
    • 2
    • 1
    • 1
    Lapin
    Clonalité
    • 196
    • 110
    Polyclonal
    Conjugué
    • 170
    • 23
    • 17
    • 11
    • 11
    • 10
    • 9
    • 7
    • 7
    • 7
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Cet anticorp STAT3 est non-conjugé
    Application
    • 224
    • 110
    • 77
    • 59
    • 51
    • 45
    • 42
    • 41
    • 27
    • 24
    • 15
    • 10
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Specificité
    STAT3 (Ab-705) antibody detects endogenous levels of total STAT3 protein.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogène
    The antiserum was produced against synthesized non-phosphopeptide derived from human STAT3 around the phosphorylation site of tyrosine 705 (A-P-YP-L-K).
  • Indications d'application
    WB: 1:500~1:1000
    IHC: 1:50~1:100.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    100ug/100ul.
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Heim: "The Jak-STAT pathway: cytokine signalling from the receptor to the nucleus." dans: Journal of receptor and signal transduction research, Vol. 19, Issue 1-4, pp. 75-120, (1999) (PubMed).

    Catlett-Falcone, Landowski, Oshiro, Turkson, Levitzki, Savino, Ciliberto, Moscinski, Fernández-Luna, Nuñez, Dalton, Jove: "Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells." dans: Immunity, Vol. 10, Issue 1, pp. 105-15, (1999) (PubMed).

    Garcia, Jove: "Activation of STAT transcription factors in oncogenic tyrosine kinase signaling." dans: Journal of biomedical science, Vol. 5, Issue 2, pp. 79-85, (1998) (PubMed).

    Takeda, Noguchi, Shi, Tanaka, Matsumoto, Yoshida, Kishimoto, Akira: "Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 8, pp. 3801-4, (1997) (PubMed).

  • Antigène
    STAT3 (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))
    Autre désignation
    STAT3 (STAT3 Produits)
    Synonymes
    anticorps 1110034C02Rik, anticorps AW109958, anticorps Aprf, anticorps APRF, anticorps HIES, anticorps Xstat3, anticorps aprf, anticorps hies, anticorps stat3, anticorps wu:fc15d02, anticorps wu:fl59g06, anticorps z-Stat3, anticorps signal transducer and activator of transcription 3, anticorps signal transduction and activation of transcription 3, anticorps signal transducer and activator of transcription 3, gene 1 L homeolog, anticorps signal transducer and activator of transcription 3 (acute-phase response factor), anticorps STAT3, anticorps stat3, anticorps Stat3, anticorps stat3.1.L
    Pathways
    Signalistation JAK/STAT, Signalisation RTK, Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Stem Cell Maintenance, Hepatitis C, Protein targeting to Nucleus, Feeding Behaviour, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor
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