TRIM25 anticorps (N-Term)

N° du produit ABIN967204

Détail du produit anti-TRIM25 anticorps

Antigène: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM25 est non-conjugé

Application: Immunohistochemistry (IHC)

Immunogène: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human TRIM25 (Tripartite motif-containing protein 25)

Information d'application

Restrictions: For Research Use only

Stockage

Stock: 4 °C

Références pour anticorps anti-TRIM25 (ABIN967204)

Inoue, Orimo, Hosoi, Kondo, Toyoshima, Kondo, Ikegami, Ouchi, Orimo, Muramatsu: "Genomic binding-site cloning reveals an estrogen-responsive gene that encodes a RING finger protein." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 23, pp. 11117-21, (1994) (PubMed).

Détails sur TRIM25

Antigène: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Autre désignation: TRIM25 (TRIM25 Produits)

Synonymes: anticorps zgc:55773, anticorps MGC130751, anticorps EFP, anticorps RNF147, anticorps Z147, anticorps ZNF147, anticorps AA960166, anticorps AL022677, anticorps Zfp147, anticorps Efp, anticorps Znf147, anticorps E3 ubiquitin/ISG15 ligase TRIM25, anticorps tripartite motif containing 25, anticorps E3 ubiquitin/ISG15 ligase TRIM25-like L homeolog, anticorps microRNA 3614, anticorps tripartite motif-containing 25, anticorps LOC100146440, anticorps trim25, anticorps LOC100490741.L, anticorps TRIM25, anticorps MIR3614, anticorps Trim25

Sujet: TRIM25 (Tripartite motif-containing protein 25) is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a Bbox type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of TRIM25 is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary TRIM25 contains 1 B30.2/SPRY domain and 1 RING-type zinc finger.
Synonyms: EFP (Estrogen-responsive finger protein), RNF147 (RING finger protein 147), ZNF147 (Zinc finger protein 147)