ASPSCR1 anticorps

N° du produit ABIN967214

Détail du produit anti-ASPSCR1 anticorps

Antigène: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Reactivité: Souris

Hôte: Veuillez nous consulter SVP

Clonalité: Monoclonal

Conjugué: Cet anticorp ASPSCR1 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: Ni-NTA purified truncated recombinant TUG expressed in E. Coli strain BL21 (DE3)

Purification: Antibodies are purified by protein A affinity chromatography

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.2%BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-ASPSCR1 (ABIN967214)

Bogan, Hendon, McKee, Tsao, Lodish: "Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking." dans: Nature, Vol. 425, Issue 6959, pp. 727-33, (2003) (PubMed).

Détails sur ASPSCR1

Antigène: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Autre désignation: TUG (ASPSCR1 Produits)

Synonymes: anticorps tug, anticorps aspl, anticorps asps, anticorps rcc17, anticorps ubxd9, anticorps aspcr1, anticorps ASPCR1, anticorps ASPL, anticorps ASPS, anticorps RCC17, anticorps TUG, anticorps UBXD9, anticorps UBXN9, anticorps 1190006K01Rik, anticorps ASPC, anticorps ASPSCR1, UBX domain containing tether for SLC2A4, anticorps alveolar soft part sarcoma chromosome region, candidate 1 S homeolog, anticorps alveolar soft part sarcoma chromosome region, candidate 1, anticorps alveolar soft part sarcoma chromosome region, candidate 1 (human), anticorps ASPSCR1, anticorps aspscr1.S, anticorps Aspscr1, anticorps aspscr1, anticorps Bm1_55980

Sujet: The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominantnegative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.

ID gène: 68938