TYK2 anticorps

N° du produit ABIN967219

Détail du produit anti-TYK2 anticorps

Antigène: TYK2 (Tyrosine Kinase 2 (TYK2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TYK2 est non-conjugé

Application: Immunohistochemistry (IHC)

Specificité: TYK2 (Ab-1054) antibody detects endogenous levels of TYK2 protein around tyrosine 1054.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized non-phosphopeptide derived from human TYK2 around the phosphorylation site of tyrosine 1054 (H-E-YP-Y-R).

Information d'application

Indications d'application: IHC: 1:50-1:100.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-TYK2 (ABIN967219)

Zheng, Hu, Quinn, Wang: "Phosphotyrosine proteomic study of interferon alpha signaling pathway using a combination of immunoprecipitation and immobilized metal affinity chromatography." dans: Molecular & cellular proteomics : MCP, Vol. 4, Issue 6, pp. 721-30, (2005) (PubMed).

Gauzzi, Velazquez, McKendry, Mogensen, Fellous, Pellegrini: "Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase." dans: The Journal of biological chemistry, Vol. 271, Issue 34, pp. 20494-500, (1996) (PubMed).

Détails sur TYK2

Antigène: TYK2 (Tyrosine Kinase 2 (TYK2))

Autre désignation: Tyk2 (TYK2 Produits)

Synonymes: anticorps JTK1, anticorps tyrosine kinase 2, anticorps TYK2, anticorps Tyk2

Pathways: Signalistation JAK/STAT, Hepatitis C