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VEGFD anticorps (Middle Region)

Figf Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN967243
  • Antigène Voir toutes VEGFD (Figf) Anticorps
    VEGFD (Figf) (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf))
    Épitope
    • 19
    • 10
    • 9
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 68
    • 21
    • 16
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 57
    • 16
    • 1
    Lapin
    Clonalité
    • 57
    • 17
    Polyclonal
    Conjugué
    • 40
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp VEGFD est non-conjugé
    Application
    • 59
    • 35
    • 30
    • 12
    • 11
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Souris, Rat (Rattus)
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Vascular endothelial growth factor D (FIGF) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
    Immunogène
    A synthetic peptide corresponding to a sequence in the middle region of human VEGFD , identical to the related rat and mouse sequences.< br/>Immunogen was affinity purified.
    Isotype
    IgG
    Top Product
    Discover our top product Figf Anticorps primaire
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Agent conservateur
    Sodium azide, Thimerosal (Merthiolate)
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.
  • Stacker, Caesar, Baldwin, Thornton, Williams, Prevo, Jackson, Nishikawa, Kubo, Achen: "VEGF-D promotes the metastatic spread of tumor cells via the lymphatics." dans: Nature medicine, Vol. 7, Issue 2, pp. 186-91, (2001) (PubMed).

    Yamada, Nezu, Shimane, Hirata: "Molecular cloning of a novel vascular endothelial growth factor, VEGF-D." dans: Genomics, Vol. 42, Issue 3, pp. 483-8, (1997) (PubMed).

  • Antigène
    VEGFD (Figf) (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf))
    Autre désignation
    Vascular endothelial growth factor D (Figf Produits)
    Synonymes
    anticorps FIGF, anticorps vegfd, anticorps vegf-d, anticorps VEGFD, anticorps AI325264, anticorps VEGF-D, anticorps Vegfd, anticorps Vegf-d, anticorps vascular endothelial growth factor D, anticorps Vascular endothelial growth factor D, anticorps VEGFD, anticorps vegfd, anticorps vegfd.L, anticorps Vegfd
    Sujet
    C-fos induced growth factor (FIGF) (or vascular endothelial growth factor D, VEGF-D) is a vascular endothelial growth factor that in humans is encoded by the FIGF gene. The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. Analyzing by Northern blotting, Yamada et al. (1997) symbolized VEGFD, was expressed as a 2. 2-kb transcript with highest expression in lung, heart, small intestine, and fetal lung, and lower levels in skeletal muscle, colon, and pancreas. And Achen et al. (1998) concluded that VEGFD was most closely related to VEGFC by virtue of the presence of N- and C-terminal extensions that were not found in other VEGF family members. Stacker et al. (2001) showed that VEGFD can induce tumor angiogenesis through VEGFR2 and tumor lymphangiogenesis through VEGFR3, whereas VEGF, which does not activate VEGFR3, induces only tumor angiogenesis.
    Pathways
    Signalisation RTK
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