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ZAP70 anticorps

ZAP70 Reactivité: Humain, Souris, Rat IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN967271
  • Antigène Voir toutes ZAP70 Anticorps
    ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
    Reactivité
    • 297
    • 129
    • 49
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 220
    • 73
    • 2
    • 2
    • 1
    Lapin
    Clonalité
    • 198
    • 99
    Polyclonal
    Conjugué
    • 147
    • 18
    • 16
    • 16
    • 12
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ZAP70 est non-conjugé
    Application
    • 202
    • 131
    • 102
    • 70
    • 53
    • 53
    • 49
    • 27
    • 27
    • 22
    • 14
    • 12
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC)
    Specificité
    Zap-70 (Ab-319) antibody detects endogenous levels of total Zap-70 protein.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogène
    The antiserum was produced against synthesized non-phosphopeptide derived from human Zap-70 around the phosphorylation site of tyrosine 319 (S-P-YP-S-D).
    Top Product
    Discover our top product ZAP70 Anticorps primaire
  • Indications d'application
    WB: 1:500~1:1000
    IHC: 1:50~1:100.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    100ug/100ul.
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Adjali, Marodon, Steinberg, Mongellaz, Thomas-Vaslin, Jacquet, Taylor, Klatzmann: "In vivo correction of ZAP-70 immunodeficiency by intrathymic gene transfer." dans: The Journal of clinical investigation, Vol. 115, Issue 8, pp. 2287-95, (2005) (PubMed).

    Salomon, Ficarro, Brill, Brinker, Phung, Ericson, Sauer, Brock, Horn, Schultz, Peters: "Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 2, pp. 443-8, (2003) (PubMed).

    Ku, Yablonski, Manser, Lim, Weiss: "A PAK1-PIX-PKL complex is activated by the T-cell receptor independent of Nck, Slp-76 and LAT." dans: The EMBO journal, Vol. 20, Issue 3, pp. 457-65, (2001) (PubMed).

    Tang, Sawasdikosol, Chang, Burakoff: "SLAP, a dimeric adapter protein, plays a functional role in T cell receptor signaling." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 17, pp. 9775-80, (1999) (PubMed).

    Williams, Irvin, Sutor, Chini, Yacyshyn, Bubeck Wardenburg, Dalton, Chan, Abraham: "Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation." dans: The EMBO journal, Vol. 18, Issue 7, pp. 1832-44, (1999) (PubMed).

    Zhao, Weiss: "Enhancement of lymphocyte responsiveness by a gain-of-function mutation of ZAP-70." dans: Molecular and cellular biology, Vol. 16, Issue 12, pp. 6765-74, (1997) (PubMed).

  • Antigène
    ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
    Autre désignation
    Zap-70 (ZAP70 Produits)
    Synonymes
    anticorps SRK, anticorps STCD, anticorps STD, anticorps TZK, anticorps ZAP-70, anticorps 70kDa, anticorps AI327364, anticorps Srk, anticorps mrtle, anticorps mur, anticorps zap70, anticorps MGC80670, anticorps MGC88962, anticorps ZAP70, anticorps zgc:110383, anticorps zeta chain of T-cell receptor associated protein kinase 70, anticorps putative tyrosine-protein kinase zap-70, anticorps zeta-chain (TCR) associated protein kinase, anticorps zeta chain of T cell receptor associated protein kinase 70, anticorps zeta-chain (TCR) associated protein kinase 70kDa, anticorps zeta chain of T cell receptor associated protein kinase 70kDa L homeolog, anticorps zeta chain of T cell receptor associated protein kinase 70kDa, anticorps tyrosine-protein kinase ZAP-70, anticorps ZAP70, anticorps Smp_149470, anticorps Zap70, anticorps zap70.L, anticorps zap70, anticorps LOC707555, anticorps LOC100342021, anticorps LOC100390922, anticorps LOC100542877
    Pathways
    TCR Signaling, Ubiquitin Proteasome Pathway
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