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Cytokeratin 7 anticorps

KRT7 Reactivité: Humain, Rat, Souris, Chien, Porc, Hamster WB, IHC Hôte: Souris Monoclonal RCK105 unconjugated
N° du produit ABIN967289
  • Antigène Voir toutes Cytokeratin 7 (KRT7) Anticorps
    Cytokeratin 7 (KRT7) (Keratin 7 (KRT7))
    Reactivité
    • 205
    • 69
    • 58
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris, Chien, Porc, Hamster
    Hôte
    • 120
    • 94
    Souris
    Clonalité
    • 121
    • 92
    • 1
    Monoclonal
    Conjugué
    • 92
    • 21
    • 15
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp Cytokeratin 7 est non-conjugé
    Application
    • 131
    • 88
    • 86
    • 86
    • 43
    • 34
    • 27
    • 26
    • 25
    • 24
    • 19
    • 15
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Marque
    BD Pharmingen™
     Réactivité croisée
    Souris, Rat (Rattus), Hamster, Chien, Porc
    Attributs du produit
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogène
    Cytokeratins from the human bladder carcinoma cell line T24
    Clone
    RCK105
    Isotype
    IgG1
    Top Product
    Discover our top product KRT7 Anticorps primaire
  • Indications d'application
    Applications include western blot analysis. Additional applications include immunohistochemistry on methanol fixed tissue, but this application is not tested.
    Commentaires

    Related Products: ABIN968535, ABIN967389

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store undiluted at 4°C.
  • Smedts, Ramaekers, Robben, Pruszczynski, van Muijen, Lane, Leigh, Vooijs: "Changing patterns of keratin expression during progression of cervical intraepithelial neoplasia." dans: The American journal of pathology, Vol. 136, Issue 3, pp. 657-68, (1990) (PubMed).

    Broers, Ramaekers, Rot, Oostendorp, Huysmans, van Muijen, Wagenaar, Vooijs: "Cytokeratins in different types of human lung cancer as monitored by chain-specific monoclonal antibodies." dans: Cancer research, Vol. 48, Issue 11, pp. 3221-9, (1988) (PubMed).

    Ramaekers, Huysmans, Schaart, Moesker, Vooijs: "Tissue distribution of keratin 7 as monitored by a monoclonal antibody." dans: Experimental cell research, Vol. 170, Issue 1, pp. 235-49, (1987) (PubMed).

  • Antigène
    Cytokeratin 7 (KRT7) (Keratin 7 (KRT7))
    Autre désignation
    Cytokeratin 7 (KRT7 Produits)
    Synonymes
    anticorps CK7, anticorps K2C7, anticorps K7, anticorps SCL, anticorps D15Wsu77e, anticorps Krt2-7, anticorps KRT7, anticorps keratin 7, anticorps KRT7, anticorps Krt7
    Sujet
    Intermediate filaments (IF) are a subset of cytoskeletal proteins which function to give overall structural integrity to the plasma membrane as well as organize cells into specific tissues. IF proteins can be divided into six major types based upon similarity in sequence. Type I and II IF proteins are designated keratins based upon whether they are acidic (I) or basic (II) and are characterized by their remarkable biochemical diversity. A subgroup of keratins, designated cytokeratins, are represented in epithelial tissues by at least 20 different polypeptides, designated 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin 7 is found in both columnar and glandular epithelium of the lung, cervix, breast, bile ducts, and in the collecting ducts in the kidney as well as mesothelium. The molecular weight of cytokeratin 7 is approximately 54 kDa in SDS/PAGE.
    Poids moléculaire
    55 kDa
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