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CD247 anticorps

CD247 Reactivité: Humain, Souris WB, IP Hôte: Souris Monoclonal 8D3 unconjugated
N° du produit ABIN967304
  • Antigène Voir toutes CD247 Anticorps
    CD247 (CD247 Molecule (CD247))
    Reactivité
    • 101
    • 47
    • 21
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 75
    • 24
    • 6
    • 1
    Souris
    Clonalité
    • 73
    • 33
    Monoclonal
    Conjugué
    • 60
    • 10
    • 8
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Cet anticorp CD247 est non-conjugé
    Application
    • 77
    • 53
    • 36
    • 14
    • 13
    • 11
    • 7
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Marque
    BD Pharmingen™
    Attributs du produit
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogène
    Human CD3zeta synthetic peptide
    Clone
    8D3
    Isotype
    IgG1
    Top Product
    Discover our top product CD247 Anticorps primaire
  • Indications d'application
    Jurkat control lysate [50 µg (1 µg/µl) is provided as a Western blot positive control (Comp. 51-16526N, store lysate at -20°C). Additional control lysate (ABIN968537) is sold separately as a ready-to-use western blot control.
    Commentaires

    Related Products: ABIN968537

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store undiluted at -20°C.
  • Antigène
    CD247 (CD247 Molecule (CD247))
    Autre désignation
    CD247 (CD247 Produits)
    Synonymes
    anticorps CD3-ZETA, anticorps CD3H, anticorps CD3Q, anticorps CD3Z, anticorps T3Z, anticorps TCRZ, anticorps 4930549J05Rik, anticorps A430104F18Rik, anticorps AW552088, anticorps Cd3, anticorps Cd3-eta, anticorps Cd3-zeta, anticorps Cd3h, anticorps Cd3z, anticorps Cd3zeta, anticorps T3z, anticorps Tcrk, anticorps Tcrz, anticorps LOC100136514, anticorps LOC100136549, anticorps LOC100305023, anticorps CD247, anticorps TCRzeta, anticorps CD247 molecule, anticorps CD247 antigen, anticorps CD3zeta-2, anticorps CD3zeta-1, anticorps Cd247 molecule, anticorps CD247, anticorps Cd247, anticorps cd3z, anticorps cd247
    Sujet
    The T-cell receptor (TCR), expressed by thymus-derived lymphocytes, is a multi-component complex responsible for recognizing antigen in the context of MHC molecules. Ti is the antigen-specific binding component of the TCR. On the majority of peripheral T lymphocytes Ti is present as a disulfide-linked alpha-beta heterodimer. A minor fraction express Ti as a gamma-delta heterodimer. The Ti subunits are Ig-like, each containing V and C regions. Ti is noncovalently associated with an invariant set of molecules referred to as the CD3 subunits. CD3 appears early in thymocyte differentiation and remains expressed on all mature T lymphocytes. In the mouse, it consists of five chains, gamma (gamma), delta (delta), epsilon (epsilon), zeta (zeta), and p21. The relative masses of the mouse CD3 chains are 21, 28, 26, 32 (dimer), and 21 kDa respectively. The 8D3 antibody recognizes the zeta chain of the human and mouse T cell antigen receptor-associated CD3 complex. It reacts with 16 kDa unphosphorylated monomers and 32 kDa unphosphorylated dimers. It does not appear to recognize 21 kDa phosphorylated monomers or 42 kDa phosphorylated dimers. A synthetic peptide corresponding to a region of human CD3zeta was used as immunogen.
    Synonyms: CD3zeta chain
    Poids moléculaire
    16 kDa, 32 kDa
    Pathways
    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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