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IL1R1 anticorps

IL1R1 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal hIL1R-M1 unconjugated
N° du produit ABIN967343
  • Antigène Voir toutes IL1R1 Anticorps
    IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
    Reactivité
    • 119
    • 68
    • 53
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 113
    • 13
    • 10
    • 5
    • 2
    • 1
    Souris
    Clonalité
    • 120
    • 24
    Monoclonal
    Conjugué
    • 61
    • 17
    • 11
    • 8
    • 8
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Cet anticorp IL1R1 est non-conjugé
    Application
    • 123
    • 64
    • 47
    • 39
    • 16
    • 15
    • 13
    • 13
    • 11
    • 8
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Marque
    BD Pharmingen™
    Attributs du produit
    1. Please refer to us for technical protocols.
    2. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Clone
    HIL1R-M1
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product IL1R1 Anticorps primaire
  • Indications d'application
    ELISA Capture: The purified HIL1R-M1 antibody (ABIN967343) is useful as a capture antibody for a sandwich ELISA for measuring human IL-1 receptor I protein levels. Purified HIL1R-M1 antibody can be paired with a biotinylated detecting antibody, with recombinant soluble human IL-1 receptor type I as the standard. Purified HIL1R-M1 antibody should be titrated between 1 - 4 µg/ml to determine its optimal concentration for ELISA capture. To obtain linear standard curves, doubling dilutions of recombinant human IL-1 receptor type I ranging from 3000 to 20 pg/ml are recommended for inclusion in each ELISA plate.
    Note: This ELISA antibody pair shows no cross-reactivity with the following recombinant human cytokines: sCD14, CD40, CD40L, IL-1Ra, IL-1RII, IL-1alpha, IL-1beta, IL-2, IL-3, IL-4, sIL-4R, IL-5, IL-6, IL-6R, IL-7, IL-8, IL-10, IL-12p40, IL-12p70, IL-13, IL-15, TNF, LT-alpha, sTNFRI, sTNFRII, IFNgamma, TRAIL, GM-CSF, TGFbeta, Trx Western Blot: The purified HIL1R-M1.1 antibody (ABIN967343) has been reported to be useful for Western blotting, however, the antibody is not routinely tested for this application.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store undiluted at 4°C.
  • Sims: "CD121a." dans: Journal of biological regulators and homeostatic agents, Vol. 14, Issue 2, pp. 133-5, (2000) (PubMed).

    Sims, Painter, Gow: "Genomic organization of the type I and type II IL-1 receptors." dans: Cytokine, Vol. 7, Issue 6, pp. 483-90, (1996) (PubMed).

    Sims, Giri, Dower: "The two interleukin-1 receptors play different roles in IL-1 actions." dans: Clinical immunology and immunopathology, Vol. 72, Issue 1, pp. 9-14, (1994) (PubMed).

  • Antigène
    IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
    Autre désignation
    CD121a (IL1R1 Produits)
    Synonymes
    anticorps CD121A, anticorps D2S1473, anticorps IL-1R-alpha, anticorps IL1R, anticorps IL1RA, anticorps P80, anticorps CD121a, anticorps CD121b, anticorps IL-iR, anticorps Il1r-1, anticorps DER4, anticorps Fit-1, anticorps Ly84, anticorps ST2L, anticorps St2, anticorps St2-rs1, anticorps T1, anticorps T1/ST2, anticorps interleukin 1 receptor type 1, anticorps interleukin 1 receptor, type I, anticorps interleukin 1 receptor-like 1, anticorps IL1R1, anticorps Il1r1, anticorps Il1rl1
    Sujet
    The HIL1R-M1 antibody reacts with recombinant and natural soluble CD121a which is also known as human IL-1 receptor type I proteins. Human IL-1 receptor type I serves as the ligand-binding chain of the IL-1 heterodimer complex. When produced by proteolytic cleavage, soluble forms of the IL-1R type I are found the circulation of healthy individuals and in excessive levels during inflammatory diseases. The human IL-1 receptor type I is also expressed predominantly by T lymphocytes, fibroblasts, and endothelial cells.
    Synonyms: IL-1 Receptor Type 1
    Pathways
    Signalisation NF-kappaB, Carbohydrate Homeostasis, Cancer Immune Checkpoints
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