Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

LAMP1 anticorps

LAMP1 Reactivité: Souris WB, IP, IHC (fro), ICS, IAC Hôte: Rat Monoclonal 1D4B unconjugated
N° du produit ABIN967382
  • Antigène Voir toutes LAMP1 Anticorps
    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
    Reactivité
    • 106
    • 65
    • 37
    • 27
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 67
    • 56
    • 24
    • 1
    Rat
    Clonalité
    • 100
    • 48
    Monoclonal
    Conjugué
    • 52
    • 15
    • 15
    • 12
    • 9
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp LAMP1 est non-conjugé
    Application
    • 92
    • 75
    • 41
    • 33
    • 26
    • 25
    • 25
    • 15
    • 15
    • 13
    • 13
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Intracellular Staining (ICS), Immunoaffinity Chromatography (IAC)
    Marque
    BD Pharmingen™
    Attributs du produit
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogène
    Plasma membrane fraction of mouse embryo NIH 3T3 cell line
    Clone
    1D4B
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product LAMP1 Anticorps primaire
  • Indications d'application
    This antibody conjugate has been tested by intracellular immunofluorescent staining ( Less or equal than 1 µg/million cells, using the Cytofix/Cytoperm™ Kit) with flow cytometric analysis to assure specificity and reactivity.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store undiluted at 4° C.
  • Rohrer, Schweizer, Russell, Kornfeld: "The targeting of Lamp1 to lysosomes is dependent on the spacing of its cytoplasmic tail tyrosine sorting motif relative to the membrane." dans: The Journal of cell biology, Vol. 132, Issue 4, pp. 565-76, (1996) (PubMed).

    Arterburn, Earles, August: "The disulfide structure of mouse lysosome-associated membrane protein 1." dans: The Journal of biological chemistry, Vol. 265, Issue 13, pp. 7419-23, (1990) (PubMed).

    Chen, Chen, DSouza, Murphy, August: "Lysosomal membrane glycoproteins: properties of LAMP-1 and LAMP-2." dans: Biochemical Society symposium, Vol. 51, pp. 97-112, (1987) (PubMed).

    Chen, Pan, DSouza, August: "Lysosome-associated membrane proteins: characterization of LAMP-1 of macrophage P388 and mouse embryo 3T3 cultured cells." dans: Archives of biochemistry and biophysics, Vol. 239, Issue 2, pp. 574-86, (1985) (PubMed).

  • Antigène
    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
    Autre désignation
    CD107a (LAMP1 Produits)
    Synonymes
    anticorps CD107a, anticorps LAMPA, anticorps LGP120, anticorps AI196048, anticorps Lamp-1, anticorps LEP100, anticorps LAMP-1, anticorps LGP-A, anticorps Lgpa, anticorps Lysosome-associated membrane protein 1, anticorps cd107a, anticorps lamp-1, anticorps lamp1, anticorps lampa, anticorps lgp120, anticorps rexp76, anticorps lysosomal associated membrane protein 1, anticorps lysosomal-associated membrane protein 1, anticorps lysosomal-associated membrane protein 1 L homeolog, anticorps LAMP1, anticorps Lamp1, anticorps lamp1.L
    Sujet
    The 1D4B antibody recognizes CD107a (Lysosome-Associated Membrane Protein 1, LAMP-1), one of the two major glycoproteins in lysosome membranes which are useful markers to distinguish lysosomes from other organelles. Mouse CD107a consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice. Several lines of evidence suggest that cell-surface mouse and human LAMP-1 glycoproteins, the expression of which may correlate with malignant transformation, participate in intercellular adhesion and adhesion to extracellular matrix.
    Synonyms: LAMP-1
    Pathways
    Autophagy
Vous êtes ici:
Support technique