Integrin beta 3 anticorps

N° du produit ABIN967485

Détail du produit anti-Integrin beta 3 anticorps

Antigène: Integrin beta 3 (ITGB3)

Reactivité: Humain, Boeuf (Vache), Babouin, Cynomolgus, Macaque rhésus

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin beta 3 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Marque: BD Pharmingen™

Attributs du produit: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: VI-PL2

Isotype: IgG1 kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4° C.

Références pour anticorps anti-Integrin beta 3 (ABIN967485)

Mason, André, Bensussan, Buckley, Civin, Clark, de Haas, Goyert, Hadam, Hart, Horejsí, Meuer, Morissey, Schwartz-Albiez, Shaw, Simmons, Uguccioni, van der Schoot, Viver, Zola: "CD antigens 2001." dans: Tissue antigens, Vol. 58, Issue 6, pp. 425-30, (2002) (PubMed).

Détails sur Integrin beta 3

Antigène: Integrin beta 3 (ITGB3)

Autre désignation: CD61 (ITGB3 Produits)

Synonymes: anticorps BDPLT16, anticorps BDPLT2, anticorps CD61, anticorps GP3A, anticorps GPIIIa, anticorps GT, anticorps INGRB3, anticorps integrin, anticorps INTB3, anticorps GPIIIA, anticorps cd61, anticorps gp3a, anticorps itgb3, anticorps itgb3.2, anticorps itgb3.1, anticorps integrin subunit beta 3, anticorps integrin beta 3, anticorps integrin subunit beta 3 L homeolog, anticorps integrin beta 3a, anticorps integrin beta 3b, anticorps ITGB3, anticorps Itgb3, anticorps itgb3.L, anticorps itgb3a, anticorps itgb3b

Sujet: Reacts with integrin beta3, a 105 kDa transmembrane glycoprotein, expressed on platelets, megakaryocytes, osteoclasts and endothelia. Integrin beta3 associates with gpIIa (CD41) to form the CD41/CD61 complex which mediates platelet adhesion and aggregation. CD61 also associates with CD51 to form the CD51/CD61 complex (vitronectin receptor). CD61 appears to bind to fibrinogen, fibronectin, vWF, vitronectin, and thrombospondin to mediate cell adhesion. This antibody is routinely tested by flow cytometric analysis.
Synonyms: Integrin beta3 Chain

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex