GRIN2B anticorps (AA 892-1051)
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- Antigène Voir toutes GRIN2B Anticorps
- GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))
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Épitope
- AA 892-1051
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Reactivité
- Humain, Rat, Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp GRIN2B est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), BioImaging (BI)
- Réactivité croisée
- Humain, Souris
- Attributs du produit
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. - Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Immunogène
- Rat NMDAR2B aa. 892-1051
- Clone
- 13-NMDAR2B
- Isotype
- IgG2b
- Top Product
- Discover our top product GRIN2B Anticorps primaire
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- Commentaires
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Related Products: ABIN968545, ABIN967389
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 250 μg/mL
- Buffer
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store undiluted at -20°C.
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Eye opening induces a rapid dendritic localization of PSD-95 in central visual neurons." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 3, pp. 1334-9, (2003) (PubMed).
: "Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain." dans: The Journal of biological chemistry, Vol. 277, Issue 1, pp. 486-91, (2002) (PubMed).
: "Overexpression of motor protein KIF17 enhances spatial and working memory in transgenic mice." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 22, pp. 14500-5, (2002) (PubMed).
: "Stimulation of Na+-K+-2Cl- cotransporter in neuronal cells by excitatory neurotransmitter glutamate." dans: The American journal of physiology, Vol. 275, Issue 3 Pt 1, pp. C772-9, (1998) (PubMed).
: "Heteromeric NMDA receptors: molecular and functional distinction of subtypes." dans: Science (New York, N.Y.), Vol. 256, Issue 5060, pp. 1217-21, (1992) (PubMed).
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Eye opening induces a rapid dendritic localization of PSD-95 in central visual neurons." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 3, pp. 1334-9, (2003) (PubMed).
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- Antigène
- GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))
- Autre désignation
- NMDAR2B (GRIN2B Produits)
- Synonymes
- anticorps NMDAR2B, anticorps GluN2B, anticorps MRD6, anticorps NR2B, anticorps hNR3, anticorps nmdar2b, anticorps nr2b, anticorps AW490526, anticorps Nmdar2b, anticorps glutamate ionotropic receptor NMDA type subunit 2B, anticorps glutamate receptor, ionotropic, N-methyl D-aspartate 2B L homeolog, anticorps glutamate receptor, ionotropic, NMDA2B (epsilon 2), anticorps GRIN2B, anticorps Grin2b, anticorps grin2b.L
- Sujet
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The majority of synapses in the central nervous system utilize glutamate as a neurotransmitter to produce rapid neuronal excitation. Glutamate has a diverse array of receptors that can be categorized into two groups: ionotropic and metabotropic. The ionotropic receptors are subdivided into two distint types: 1) receptors for N-methyl D-aspartate (NMDAR) and 2) non-NMDA receptors for AMPA and kainate. Three types of NMDAR2 have been identified: NR2A, NR2B, and NR2C. NR2A and NR2B contain a C-terminal extension (>600 amino acids) that has small scattered regions of conserved sequence. The three NR2 mRNAs show overlapping, differential expression patterns in the rat brain. NR2B has been reported to be expressed in the forebrain, thalamic nuclei, amygdaloid nuclei, caudateputamen, and in restricted regions of the olfactory bulb. This antibody is routinely tested by western blot analysis.
Synonyms: N-Methyl-D-Aspartate Receptor 2B - Poids moléculaire
- 180 kDa
- Pathways
- Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity
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