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XIAP anticorps (AA 268-426)

XIAP Reactivité: Humain, Souris, Chien WB, IHC, IF, IP Hôte: Souris Monoclonal 28-hILP-XIAP unconjugated
N° du produit ABIN968132
  • Antigène Voir toutes XIAP Anticorps
    XIAP (X-Linked Inhibitor of Apoptosis (XIAP))
    Épitope
    • 16
    • 12
    • 12
    • 9
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 268-426
    Reactivité
    • 90
    • 48
    • 33
    • 3
    • 2
    • 2
    • 1
    Humain, Souris, Chien
    Hôte
    • 76
    • 15
    • 1
    Souris
    Clonalité
    • 77
    • 13
    Monoclonal
    Conjugué
    • 54
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp XIAP est non-conjugé
    Application
    • 78
    • 39
    • 33
    • 18
    • 15
    • 15
    • 13
    • 13
    • 7
    • 7
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
     Réactivité croisée
    Chien, Souris
    Attributs du produit
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogène
    Human hILP/XIAP aa. 268-426
    Clone
    28-hILP-XIAP
    Isotype
    IgG1
    Top Product
    Discover our top product XIAP Anticorps primaire
  • Commentaires

    Related Products: ABIN968535, ABIN967389

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store undiluted at -20° C.
  • Birkey Reffey, Wurthner, Parks, Roberts, Duckett: "X-linked inhibitor of apoptosis protein functions as a cofactor in transforming growth factor-beta signaling." dans: The Journal of biological chemistry, Vol. 276, Issue 28, pp. 26542-9, (2001) (PubMed).

    Lee, Shacter: "Fas aggregation does not correlate with Fas-mediated apoptosis." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 1, pp. 82-9, (2001) (PubMed).

    Wang, Gastman, Wieckowski, Goldstein, Rabinovitz, Yin, Rabinowich: "Apoptosis-resistant mitochondria in T cells selected for resistance to Fas signaling." dans: The Journal of biological chemistry, Vol. 276, Issue 5, pp. 3610-9, (2001) (PubMed).

    Yang, Fang, Jensen, Weissman, Ashwell: "Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli." dans: Science (New York, N.Y.), Vol. 288, Issue 5467, pp. 874-7, (2000) (PubMed).

    Duckett, Nava, Gedrich, Clem, Van Dongen, Gilfillan, Shiels, Hardwick, Thompson: "A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors." dans: The EMBO journal, Vol. 15, Issue 11, pp. 2685-94, (1996) (PubMed).

  • Antigène
    XIAP (X-Linked Inhibitor of Apoptosis (XIAP))
    Autre désignation
    hILP (XIAP Produits)
    Synonymes
    anticorps API3, anticorps BIRC4, anticorps IAP-3, anticorps ILP1, anticorps MIHA, anticorps XLP2, anticorps hIAP-3, anticorps hIAP3, anticorps api3, anticorps birc4, anticorps ilp1, anticorps miha, anticorps xlp2, anticorps xxiap, anticorps 1110015C02Rik, anticorps Aipa, anticorps Api3, anticorps Birc4, anticorps IAP3, anticorps ILP-1, anticorps mXIAP, anticorps riap3, anticorps fb73d01, anticorps wu:fb73d01, anticorps zgc:91873, anticorps BIRC8, anticorps X-linked inhibitor of apoptosis, anticorps X-linked inhibitor of apoptosis L homeolog, anticorps XIAP, anticorps xiap, anticorps xiap.L, anticorps Xiap
    Sujet
    Apoptosis is a genetically programmed, selective process of cell death that occurs during normal cell differentiation and development of multicellular organisms. Viruses depend on the biosynthetic machinery of their host cell for the production of progeny and survival. Therefore, many viruses encode proteins that protect the cell from apoptosis. hILP (human IAP-like protein) is a human homologue of the viral IAP (Inhibitor of Apoptosis Protein). hILP is a widely expressed cytoplasmic protein of 497 amino acids with three BIR (Baculovirus IAP repeats) domains and a C-terminal RING finger domain. hILP-transfected cells are protected against the apoptotic effects of Sindbis virus infection and ICE (interleukin-1beta converting enzyme) expression. This product is sold under license from Aegera Therapeutics, Inc. This antibody is routinely tested by western blot analysis.
    Synonyms: hILP
    Poids moléculaire
    57 kDa
    Pathways
    Apoptose, Caspase Cascade in Apoptosis, Transition Metal Ion Homeostasis
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