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DYNLL1 anticorps (AA 1-89)

DYNLL1 Reactivité: Humain, Rat WB, IF, IP, IHC (f) Hôte: Souris Monoclonal 4-PIN unconjugated
N° du produit ABIN968140
  • Antigène Voir toutes DYNLL1 Anticorps
    DYNLL1 (Dynein, Light Chain, LC8-Type 1 (DYNLL1))
    Épitope
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-89
    Reactivité
    • 40
    • 29
    • 27
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    Humain, Rat
    Hôte
    • 36
    • 3
    • 2
    Souris
    Clonalité
    • 26
    • 15
    Monoclonal
    Conjugué
    • 21
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp DYNLL1 est non-conjugé
    Application
    • 22
    • 12
    • 10
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
     Réactivité croisée
    Humain
    Attributs du produit
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogène
    Rat PIN aa. 1-89
    Clone
    4-PIN
    Isotype
    IgG1
    Top Product
    Discover our top product DYNLL1 Anticorps primaire
  • Commentaires

    Related Products: ABIN968545, ABIN967389

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store undiluted at -20° C.
  • Dick, Ray, Salz, Chia: "Cytoplasmic dynein (ddlc1) mutations cause morphogenetic defects and apoptotic cell death in Drosophila melanogaster." dans: Molecular and cellular biology, Vol. 16, Issue 5, pp. 1966-77, (1996) (PubMed).

    Jaffrey, Snyder: "PIN: an associated protein inhibitor of neuronal nitric oxide synthase." dans: Science (New York, N.Y.), Vol. 274, Issue 5288, pp. 774-7, (1996) (PubMed).

  • Antigène
    DYNLL1 (Dynein, Light Chain, LC8-Type 1 (DYNLL1))
    Autre désignation
    PIN (DYNLL1 Produits)
    Synonymes
    anticorps DLC1, anticorps DLC8, anticorps DNCL1, anticorps DNCLC1, anticorps LC8, anticorps LC8a, anticorps PIN, anticorps hdlc1, anticorps dynll2, anticorps wu:fd56c09, anticorps zgc:73406, anticorps Dlc8, anticorps Dnclc1, anticorps Pin, anticorps 8kDLC, anticorps lc8, anticorps dlc1, anticorps dlc8, anticorps lc8a, anticorps dncl1, anticorps dnclc1, anticorps dynll1a, anticorps MGC68763, anticorps CDLC2, anticorps dynll1, anticorps dynll1b, anticorps pin, anticorps MGC89636, anticorps dynein light chain LC8-type 1, anticorps dynein, light chain, LC8-type 1, anticorps dynein light chain LC8-type 1 S homeolog, anticorps dynein light chain LC8-type 1 L homeolog, anticorps Dynein light chain 1, cytoplasmic, anticorps DYNLL1, anticorps dynll1, anticorps Dynll1, anticorps dynll1.S, anticorps dynll1.L, anticorps dlc-1
    Sujet
    PIN (protein inhibitor of nNOS) is a small protein of 89 amino acids initially described as a light chain subunit of dynein and as an inhibitor of the neuronal nitric oxide synthase isoform (nNOS). In vitro, PIN has been reported to bind to a unique nNOS domain encompassing amino acids 163-245. PIN inhibits nNOS activity and blocks the formation of the active nNOS dimer. Although ubiquitously expressed, PIN levels are reportedly highest in brain and testis. Immunolocalization studies in Drosophila melanogaster detected a cytoplasmic distribution of PIN. Partial-loss-of-function of PIN resulted in morphologic and developmental changes in the bristles, wings, and female sterility of D. melanogaster. Deletion of PIN resulted in lethality with the characteristic morphology of apoptotic cells. This antibody is routinely tested by western blot analysis.
    Synonyms: Protein Inhibitor of nNOS
    Poids moléculaire
    10 kDa
    Pathways
    M Phase, Tube Formation, Positive Regulation of Endopeptidase Activity
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