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NAT1 anticorps (AA 672-830)

NAT1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien WB, IHC, IP, IF Hôte: Souris Monoclonal 35-T1 unconjugated
N° du produit ABIN968148
  • Antigène Voir toutes NAT1 Anticorps
    NAT1 (N-Acetyltransferase 1 (Arylamine N-Acetyltransferase) (NAT1))
    Épitope
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 672-830
    Reactivité
    Humain, Souris, Rat, Boeuf (Vache), Chien
    Hôte
    • 43
    • 3
    • 1
    Souris
    Clonalité
    • 45
    • 2
    Monoclonal
    Conjugué
    • 23
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NAT1 est non-conjugé
    Application
    • 32
    • 24
    • 9
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
     Réactivité croisée
    Souris, Rat (Rattus), Chien, Boeuf (Vache)
    Attributs du produit
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogène
    Human NAT1 aa. 672-830
    Clone
    35-T1
    Isotype
    IgG1
    Top Product
    Discover our top product NAT1 Anticorps primaire
  • Commentaires

    Related Products: ABIN968535, ABIN967389

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store undiluted at -20° C.
  • Henis-Korenblit, Strumpf, Goldstaub, Kimchi: "A novel form of DAP5 protein accumulates in apoptotic cells as a result of caspase cleavage and internal ribosome entry site-mediated translation." dans: Molecular and cellular biology, Vol. 20, Issue 2, pp. 496-506, (2000) (PubMed).

    Yamanaka, Poksay, Arnold, Innerarity: "A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme." dans: Genes & development, Vol. 11, Issue 3, pp. 321-33, (1997) (PubMed).

  • Antigène
    NAT1 (N-Acetyltransferase 1 (Arylamine N-Acetyltransferase) (NAT1))
    Autre désignation
    NAT1 (NAT1 Produits)
    Synonymes
    anticorps AAC1, anticorps MNAT, anticorps NAT-1, anticorps NATI, anticorps Nat-1, anticorps Nat, anticorps NAT1, anticorps AT-I, anticorps N-acetyltransferase 1, anticorps N-acetyl transferase 1, anticorps N-acetyltransferase 1 (arylamine N-acetyltransferase), anticorps arylamine N-acetyltransferase 1-like, anticorps NAT1, anticorps Nat1, anticorps LOC101095575
    Sujet
    EIF-4 proteins are required for recognition of mRNA and acceleration of protein translation. This group of proteins consists of the RNA helicase eIF-4A, the RNA-binding protein eIF-4B, the cap-binding protein eIF-4E, and eIF-4G (p220). NAT1 (Novel APOBEC-1 Target no. 1), also known as DAP-5 (Death Associated Protein -5), is homologous to eIF-4G. Amino acid sequence comparison of NAT1 and eIF-4 shows that NAT1 lacks an eIF-4G N-terminal region. This region mediates eIF-4G association with eIF-4E. The highest degree of homology is within the central portions of NAT1 and eIF-4G, while the lowest degree of homology occurs at the C-terminus. NAT1 more closely resembles a cleaved form of eIF-4G that is involved in cap-independent translation. It is thought that NAT1 is involved in the repression of translation via its inhibition of both cap-dependent and cap-independent translation.
    Synonyms: Novel APOBEC-1 Target no. 1, DAP-5, Death Associated Protein -5
    Poids moléculaire
    100 kDa
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