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SCARB1 anticorps (AA 104-294)

SCARB1 Reactivité: Humain WB, IF Hôte: Souris Monoclonal 25-CLA unconjugated
N° du produit ABIN968230
  • Antigène Voir toutes SCARB1 Anticorps
    SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))
    Épitope
    • 11
    • 10
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 104-294
    Reactivité
    • 54
    • 30
    • 29
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 51
    • 11
    • 2
    Souris
    Clonalité
    • 42
    • 22
    Monoclonal
    Conjugué
    • 37
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp SCARB1 est non-conjugé
    Application
    • 40
    • 19
    • 15
    • 12
    • 12
    • 9
    • 8
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Attributs du produit
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogène
    Human CLA-1 aa. 104-294
    Clone
    25-CLA
    Isotype
    IgG1
    Top Product
    Discover our top product SCARB1 Anticorps primaire
  • Commentaires

    Related Products: ABIN968535, ABIN967389

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store undiluted at -20°C.
  • Lasley, Narayan, Uittenbogaard, Smart: "Activated cardiac adenosine A(1) receptors translocate out of caveolae." dans: The Journal of biological chemistry, Vol. 275, Issue 6, pp. 4417-21, (2000) (PubMed).

    Kozarsky, Donahee, Rigotti, Iqbal, Edelman, Krieger: "Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels." dans: Nature, Vol. 387, Issue 6631, pp. 414-7, (1997) (PubMed).

    Acton, Rigotti, Landschulz, Xu, Hobbs, Krieger: "Identification of scavenger receptor SR-BI as a high density lipoprotein receptor." dans: Science (New York, N.Y.), Vol. 271, Issue 5248, pp. 518-20, (1996) (PubMed).

    Calvo, Vega: "Identification, primary structure, and distribution of CLA-1, a novel member of the CD36/LIMPII gene family." dans: The Journal of biological chemistry, Vol. 268, Issue 25, pp. 18929-35, (1993) (PubMed).

  • Antigène
    SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))
    Autre désignation
    CLA-1 (SCARB1 Produits)
    Synonymes
    anticorps cb1015, anticorps SCARB1, anticorps Scarb1, anticorps CD36L1, anticorps CLA-1, anticorps CLA1, anticorps HDLQTL6, anticorps SR-BI, anticorps SRB1, anticorps AI120173, anticorps CD36, anticorps Cd36l1, anticorps Cla-1, anticorps Cla1, anticorps D5Ertd460e, anticorps Hdlq1, anticorps Hlb398, anticorps SR-B1, anticorps SRBI, anticorps Srb1, anticorps mSR-BI, anticorps scavenger receptor class B, member 1, anticorps scavenger receptor class B member 1, anticorps scarb1, anticorps SCARB1, anticorps Scarb1, anticorps CpipJ_CPIJ014332, anticorps CpipJ_CPIJ019101
    Sujet
    CLA-1 (CD36 and LIMPII Analogous-1) is member of a novel gene family that includes CD36, LIMPII, and SR-BI. CD36 is a cell surface glycoprotein that binds to collagen type I and thrombospondin. LIMPII (lysosomal integral membrane protein II), as its name suggests, is expressed on the membrane of lysosomes. SR-BI (scavenger receptor type B class I) is involved in the selective uptake of cholesterol esters. These proteins include two membrane-anchoring regions, two short cytoplasmic tails, and a large extracellular/luminal domain. CLA-1 mRNA is detected in a wide range of tissues including adrenal glands, liver, and testis. Its expression and similarity with other family members suggest it may play a role in HDL metabolism. However, identification of the CLA-1 receptor on monocytes indicates additional CLA-1 functions in leukocytes.
    Synonyms: CD36 and LIMPII Analogous-1
    Poids moléculaire
    80 kDa
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism, SARS-CoV-2 Protein Interactome
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