ADIPOQ anticorps (AA 1-247)
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- Antigène Voir toutes ADIPOQ Anticorps
- ADIPOQ (Adiponectin (ADIPOQ))
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Épitope
- AA 1-247
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp ADIPOQ est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Attributs du produit
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Immunogène
- Human Acrp30 aa. 1-247
- Clone
- 31-Acrp30
- Isotype
- IgG2a
- Top Product
- Discover our top product ADIPOQ Anticorps primaire
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- Commentaires
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Related Products: ABIN967389
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 250 μg/mL
- Buffer
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store undiluted at -20°C.
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Two compartments for insulin-stimulated exocytosis in 3T3-L1 adipocytes defined by endogenous ACRP30 and GLUT4." dans: The Journal of cell biology, Vol. 146, Issue 3, pp. 609-20, (1999) (PubMed).
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Two compartments for insulin-stimulated exocytosis in 3T3-L1 adipocytes defined by endogenous ACRP30 and GLUT4." dans: The Journal of cell biology, Vol. 146, Issue 3, pp. 609-20, (1999) (PubMed).
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- Antigène
- ADIPOQ (Adiponectin (ADIPOQ))
- Autre désignation
- Acrp30 (ADIPOQ Produits)
- Synonymes
- anticorps ADP, anticorps DCAF9, anticorps 6720489L24Rik, anticorps 9330209L04Rik, anticorps Adp, anticorps Mamdc1, anticorps RNSVSP4U, anticorps SVSIV1, anticorps Svp4, anticorps ACDC, anticorps ACRP30, anticorps ADIPQTL1, anticorps ADPN, anticorps APM-1, anticorps APM1, anticorps GBP28, anticorps apM-1, anticorps 30kDa, anticorps APN, anticorps Acdc, anticorps Acrp30, anticorps Ad, anticorps adipo, anticorps apM1, anticorps ADN, anticorps acrpl, anticorps adipo-b, anticorps adipoql, anticorps zgc:153584, anticorps adipoq, anticorps WD and tetratricopeptide repeats 1, anticorps MAM domain containing glycosylphosphatidylinositol anchor 2, anticorps seminal vesicle secretory protein 4, anticorps adiponectin, C1Q and collagen domain containing, anticorps adiponectin, C1Q and collagen domain containing, b, anticorps adiponectin, C1Q and collagen domain containing L homeolog, anticorps WDTC1, anticorps Mdga2, anticorps Svs4, anticorps ADIPOQ, anticorps Adipoq, anticorps adipoqb, anticorps adipoq.L
- Sujet
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Adipocytes express a variety of proteins that function in the homeostatic control of glucose and lipid metabolism. Insulin regulates the translocation and secretion of many of these adipocyte proteins in response to homeostatic changes in energy balance. Both adipsin and adipocyte complement-related protein of 30 kDa (Acrp30) are secretory proteins whose secretion from adipocytes is enhanced by insulin stimulation. Acrp30 contains N-terminal collagen repeats and a globular C-terminal domain. It is homologous to collagen type VIII and X and to complement factor C1q. Also, it forms homo-oligomeric structures of 90 and 300 kDa. The expression of Acrp30 increases 100 fold during adipocyte differentiation and it is commonly found in serum. Insulin stimulation of 3T3-L1 fibroblasts leads to a 4-fold increase in Acrp30 secretion. This secretion is regulated by PI3-kinase activity and may involve a secretory pathway that is distinct from other insulin-regulated secretory pathways, such as that involved with the translocation of glucose transporters and transferrin receptors. Thus, Acrp30 is an adipocyte secretory protein that functions in the regulation of energy homeostasis.
Synonyms: Adiponectin - Poids moléculaire
- 30 kDa
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